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Page 1
Increased atrial effectiveness of flecainide conferred by altered biophysical properties of sodium channels.
O' Brien S, Holmes AP, Johnson DM, Kabir SN, O' Shea C, O' Reilly M, Avezzu A, Reyat JS, Hall AW, Apicella C, Ellinor PT, Niederer S, Tucker NR, Fabritz L, Kirchhof P, Pavlovic D. O' Brien S, et al. Among authors: kabir sn. J Mol Cell Cardiol. 2022 May;166:23-35. doi: 10.1016/j.yjmcc.2022.01.009. Epub 2022 Feb 1. J Mol Cell Cardiol. 2022. PMID: 35114252 Free article.
Cardiac optical mapping - State-of-the-art and future challenges.
O'Shea C, Kabir SN, Holmes AP, Lei M, Fabritz L, Rajpoot K, Pavlovic D. O'Shea C, et al. Among authors: kabir sn. Int J Biochem Cell Biol. 2020 Sep;126:105804. doi: 10.1016/j.biocel.2020.105804. Epub 2020 Jul 15. Int J Biochem Cell Biol. 2020. PMID: 32681973 Free PMC article. Review.
Reduced left atrial cardiomyocyte PITX2 and elevated circulating BMP10 predict atrial fibrillation after ablation.
Reyat JS, Chua W, Cardoso VR, Witten A, Kastner PM, Kabir SN, Sinner MF, Wesselink R, Holmes AP, Pavlovic D, Stoll M, Kääb S, Gkoutos GV, de Groot JR, Kirchhof P, Fabritz L. Reyat JS, et al. Among authors: kabir sn. JCI Insight. 2020 Aug 20;5(16):e139179. doi: 10.1172/jci.insight.139179. JCI Insight. 2020. PMID: 32814717 Free PMC article. Clinical Trial.
Atrial resting membrane potential confers sodium current sensitivity to propafenone, flecainide and dronedarone.
Holmes AP, Saxena P, Kabir SN, O'Shea C, Kuhlmann SM, Gupta S, Fobian D, Apicella C, O'Reilly M, Syeda F, Reyat JS, Smith GL, Workman AJ, Pavlovic D, Fabritz L, Kirchhof P. Holmes AP, et al. Among authors: kabir sn. Heart Rhythm. 2021 Jul;18(7):1212-1220. doi: 10.1016/j.hrthm.2021.03.016. Epub 2021 Mar 16. Heart Rhythm. 2021. PMID: 33737232 Free PMC article.
Diminished PLK2 Induces Cardiac Fibrosis and Promotes Atrial Fibrillation.
Künzel SR, Hoffmann M, Weber S, Künzel K, Kämmerer S, Günscht M, Klapproth E, Rausch JSE, Sadek MS, Kolanowski T, Meyer-Roxlau S, Piorkowski C, Tugtekin SM, Rose-John S, Yin X, Mayr M, Kuhlmann JD, Wimberger P, Grützmann K, Herzog N, Küpper JH, O'Reilly M, Kabir SN, Sommerfeld LC, Guan K, Wielockx B, Fabritz L, Nattel S, Ravens U, Dobrev D, Wagner M, El-Armouche A. Künzel SR, et al. Among authors: kabir sn. Circ Res. 2021 Oct;129(8):804-820. doi: 10.1161/CIRCRESAHA.121.319425. Epub 2021 Aug 26. Circ Res. 2021. PMID: 34433292 Free PMC article.
High resolution optical mapping of cardiac electrophysiology in pre-clinical models.
O'Shea C, Winter J, Kabir SN, O'Reilly M, Wells SP, Baines O, Sommerfeld LC, Correia J, Lei M, Kirchhof P, Holmes AP, Fabritz L, Rajpoot K, Pavlovic D. O'Shea C, et al. Among authors: kabir sn. Sci Data. 2022 Mar 31;9(1):135. doi: 10.1038/s41597-022-01253-1. Sci Data. 2022. PMID: 35361792 Free PMC article.
Familial atrial fibrillation mutation M1875T-SCN5A increases early sodium current and dampens the effect of flecainide.
O'Reilly M, Sommerfeld LC, O'Shea C, Broadway-Stringer S, Andaleeb S, Reyat JS, Kabir SN, Stastny D, Malinova A, Delbue D, Fortmueller L, Gehmlich K, Pavlovic D, Skryabin BV, Holmes AP, Kirchhof P, Fabritz L. O'Reilly M, et al. Among authors: kabir sn. Europace. 2023 Mar 30;25(3):1152-1161. doi: 10.1093/europace/euac218. Europace. 2023. PMID: 36504385 Free PMC article.
Reduced plakoglobin increases the risk of sodium current defects and atrial conduction abnormalities in response to androgenic anabolic steroid abuse.
Sommerfeld LC, Holmes AP, Yu TY, O'Shea C, Kavanagh DM, Pike JM, Wright T, Syeda F, Aljehani A, Kew T, Cardoso VR, Kabir SN, Hepburn C, Menon PR, Broadway-Stringer S, O'Reilly M, Witten A, Fortmueller L, Lutz S, Kulle A, Gkoutos GV, Pavlovic D, Arlt W, Lavery GG, Steeds R, Gehmlich K, Stoll M, Kirchhof P, Fabritz L. Sommerfeld LC, et al. Among authors: kabir sn. J Physiol. 2024 Feb 12. doi: 10.1113/JP284597. Online ahead of print. J Physiol. 2024. PMID: 38345865
56 results