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Year Number of Results
2019 2
2020 3
2021 2
2023 5
2024 0

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12 results

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Page 1
Inter-cellular CRISPR screens reveal regulators of cancer cell phagocytosis.
Kamber RA, Nishiga Y, Morton B, Banuelos AM, Barkal AA, Vences-Catalán F, Gu M, Fernandez D, Seoane JA, Yao D, Liu K, Lin S, Spees K, Curtis C, Jerby-Arnon L, Weissman IL, Sage J, Bassik MC. Kamber RA, et al. Among authors: spees k. Nature. 2021 Sep;597(7877):549-554. doi: 10.1038/s41586-021-03879-4. Epub 2021 Sep 8. Nature. 2021. PMID: 34497417 Free PMC article.
Large-scale mapping and mutagenesis of human transcriptional effector domains.
DelRosso N, Tycko J, Suzuki P, Andrews C, Aradhana, Mukund A, Liongson I, Ludwig C, Spees K, Fordyce P, Bassik MC, Bintu L. DelRosso N, et al. Among authors: spees k. Nature. 2023 Apr;616(7956):365-372. doi: 10.1038/s41586-023-05906-y. Epub 2023 Apr 5. Nature. 2023. PMID: 37020022 Free PMC article.
High-Throughput Discovery and Characterization of Human Transcriptional Effectors.
Tycko J, DelRosso N, Hess GT, Aradhana, Banerjee A, Mukund A, Van MV, Ego BK, Yao D, Spees K, Suzuki P, Marinov GK, Kundaje A, Bassik MC, Bintu L. Tycko J, et al. Among authors: spees k. Cell. 2020 Dec 23;183(7):2020-2035.e16. doi: 10.1016/j.cell.2020.11.024. Epub 2020 Dec 15. Cell. 2020. PMID: 33326746 Free PMC article.
Death-seq identifies regulators of cell death and senolytic therapies.
Colville A, Liu JY, Rodriguez-Mateo C, Thomas S, Ishak HD, Zhou R, Klein JDD, Morgens DW, Goshayeshi A, Salvi JS, Yao D, Spees K, Dixon SJ, Liu C, Rhee JW, Lai C, Wu JC, Bassik MC, Rando TA. Colville A, et al. Among authors: spees k. Cell Metab. 2023 Oct 3;35(10):1814-1829.e6. doi: 10.1016/j.cmet.2023.08.008. Epub 2023 Sep 11. Cell Metab. 2023. PMID: 37699398
CRISPR screens in cancer spheroids identify 3D growth-specific vulnerabilities.
Han K, Pierce SE, Li A, Spees K, Anderson GR, Seoane JA, Lo YH, Dubreuil M, Olivas M, Kamber RA, Wainberg M, Kostyrko K, Kelly MR, Yousefi M, Simpkins SW, Yao D, Lee K, Kuo CJ, Jackson PK, Sweet-Cordero A, Kundaje A, Gentles AJ, Curtis C, Winslow MM, Bassik MC. Han K, et al. Among authors: spees k. Nature. 2020 Apr;580(7801):136-141. doi: 10.1038/s41586-020-2099-x. Epub 2020 Mar 11. Nature. 2020. PMID: 32238925 Free PMC article.
SLC12A9 is a lysosome-detoxifying ammonium - chloride co-transporter.
Levin-Konigsberg R, Mitra K, Nigam A, Spees K, Hivare P, Liu K, Kundaje A, Krishnan Y, Bassik MC. Levin-Konigsberg R, et al. Among authors: spees k. bioRxiv [Preprint]. 2023 May 22:2023.05.22.541801. doi: 10.1101/2023.05.22.541801. bioRxiv. 2023. PMID: 37292735 Free PMC article. Preprint.
A genome-wide atlas of co-essential modules assigns function to uncharacterized genes.
Wainberg M, Kamber RA, Balsubramani A, Meyers RM, Sinnott-Armstrong N, Hornburg D, Jiang L, Chan J, Jian R, Gu M, Shcherbina A, Dubreuil MM, Spees K, Meuleman W, Snyder MP, Bassik MC, Kundaje A. Wainberg M, et al. Among authors: spees k. Nat Genet. 2021 May;53(5):638-649. doi: 10.1038/s41588-021-00840-z. Epub 2021 Apr 15. Nat Genet. 2021. PMID: 33859415 Free PMC article.
Mitigation of off-target toxicity in CRISPR-Cas9 screens for essential non-coding elements.
Tycko J, Wainberg M, Marinov GK, Ursu O, Hess GT, Ego BK, Aradhana, Li A, Truong A, Trevino AE, Spees K, Yao D, Kaplow IM, Greenside PG, Morgens DW, Phanstiel DH, Snyder MP, Bintu L, Greenleaf WJ, Kundaje A, Bassik MC. Tycko J, et al. Among authors: spees k. Nat Commun. 2019 Sep 6;10(1):4063. doi: 10.1038/s41467-019-11955-7. Nat Commun. 2019. PMID: 31492858 Free PMC article.
12 results