Kamiyama K - Search Results

1

Design and synthesis of novel human epidermal growth factor receptor 2 (HER2)/epidermal growth factor receptor (EGFR) dual inhibitors bearing a pyrrolo[3,2-d]pyrimidine scaffold.

Ishikawa T, Seto M, Banno H, Kawakita Y, Oorui M, Taniguchi T, Ohta Y, Tamura T, Nakayama A, Miki H, Kamiguchi H, Tanaka T, Habuka N, Sogabe S, Yano J, Aertgeerts K, Kamiyama K. Ishikawa T, et al. Among authors: kamiyama k. J Med Chem. 2011 Dec 8;54(23):8030-50. doi: 10.1021/jm2008634. Epub 2011 Nov 4. J Med Chem. 2011. PMID: 22003817

2

Design, synthesis, and evaluation of 5-methyl-4-phenoxy-5H-pyrrolo[3,2-d]pyrimidine derivatives: novel VEGFR2 kinase inhibitors binding to inactive kinase conformation.

Oguro Y, Miyamoto N, Okada K, Takagi T, Iwata H, Awazu Y, Miki H, Hori A, Kamiyama K, Imamura S. Oguro Y, et al. Among authors: kamiyama k. Bioorg Med Chem. 2010 Oct 15;18(20):7260-73. doi: 10.1016/j.bmc.2010.08.017. Epub 2010 Aug 13. Bioorg Med Chem. 2010. PMID: 20833055

3

N-phenyl-N'-[4-(5H-pyrrolo[3,2-d]pyrimidin-4-yloxy)phenyl]ureas as novel inhibitors of VEGFR and FGFR kinases.

Oguro Y, Miyamoto N, Takagi T, Okada K, Awazu Y, Miki H, Hori A, Kamiyama K, Imamura S. Oguro Y, et al. Among authors: kamiyama k. Bioorg Med Chem. 2010 Oct 15;18(20):7150-63. doi: 10.1016/j.bmc.2010.08.042. Epub 2010 Aug 25. Bioorg Med Chem. 2010. PMID: 20833551

4

Design and synthesis of pyrrolo[3,2-d]pyrimidine HER2/EGFR dual inhibitors: improvement of the physicochemical and pharmacokinetic profiles for potent in vivo anti-tumor efficacy.

Kawakita Y, Miwa K, Seto M, Banno H, Ohta Y, Tamura T, Yusa T, Miki H, Kamiguchi H, Ikeda Y, Tanaka T, Kamiyama K, Ishikawa T. Kawakita Y, et al. Among authors: kamiyama k. Bioorg Med Chem. 2012 Oct 15;20(20):6171-80. doi: 10.1016/j.bmc.2012.08.002. Epub 2012 Aug 25. Bioorg Med Chem. 2012. PMID: 22980219

5

Studies on anti-MRSA parenteral cephalosporins. III. Synthesis and antibacterial activity of 7beta-[2-(5-amino-1,2,4-thiadiazol-3-yl)-2(Z)-alkoxyiminoacetamido-3.

Ishikawa T, Kamiyama K, Nakayama Y, Iizawa Y, Okonogi K, Miyake A. Ishikawa T, et al. Among authors: kamiyama k. J Antibiot (Tokyo). 2001 Mar;54(3):257-77. doi: 10.7164/antibiotics.54.257. J Antibiot (Tokyo). 2001. PMID: 11372783 Free article.

6

Studies on anti-MRSA parenteral cephalosporins. II. Synthesis and antibacterial activity of 7beta-[2-(5-amino-1,2,4- thiadiazol-3-yl)-2(Z)-alkoxyiminoacetamido]-3-(substituted imidaz.

Ishikawa T, Kamiyama K, Matsunaga N, Tawada H, Iizawa Y, Okonogi K, Miyake A. Ishikawa T, et al. Among authors: kamiyama k. J Antibiot (Tokyo). 2000 Oct;53(10):1071-85. doi: 10.7164/antibiotics.53.1071. J Antibiot (Tokyo). 2000. PMID: 11132951 Free article.

7

Development of a stereoselective practical synthetic route to indolmycin, a candidate anti-H. pylori agent.

Hasuoka A, Nakayama Y, Adachi M, Kamiguchi H, Kamiyama K. Hasuoka A, et al. Among authors: kamiyama k. Chem Pharm Bull (Tokyo). 2001 Dec;49(12):1604-8. doi: 10.1248/cpb.49.1604. Chem Pharm Bull (Tokyo). 2001. PMID: 11767081 Free article.

8

Studies on anti-MRSA parenteral cephalosporins. IV. A novel water-soluble N-phosphono type prodrug for parental administration.

Ishikawa T, Nakayama Y, Tomimoto M, Niwa SI, Kamiyama K, Hashiguchi S, Iizawa Y, Okonogi K, Miyake A. Ishikawa T, et al. Among authors: kamiyama k. J Antibiot (Tokyo). 2001 Apr;54(4):364-74. doi: 10.7164/antibiotics.54.364. J Antibiot (Tokyo). 2001. PMID: 11426661 Free article.

9

Total synthesis of novel antibiotics pyloricidin A, B and C and their application in the study of pyloricidin derivatives.

Hasuoka A, Nishikimi Y, Nakayama Y, Kamiyama K, Nakao M, Miyagawa K, Nishimura O, Fujino M. Hasuoka A, et al. Among authors: kamiyama k. J Antibiot (Tokyo). 2002 Feb;55(2):191-203. doi: 10.7164/antibiotics.55.191. J Antibiot (Tokyo). 2002. PMID: 12003001 Free article.

10

Synthesis and anti-Helicobacter pylori activity of pyloricidin derivatives I. Structure-activity relationships on the terminal peptidic moiety.

Hasuoka A, Nishikimi Y, Nakayama Y, Kamiyama K, Nakao M, Miyagawa K, Nishimura O, Fujino M. Hasuoka A, et al. Among authors: kamiyama k. J Antibiot (Tokyo). 2002 Mar;55(3):322-36. doi: 10.7164/antibiotics.55.322. J Antibiot (Tokyo). 2002. PMID: 12014449 Free article.

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