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Induction of osteoclast differentiation by Runx2 through receptor activator of nuclear factor-kappa B ligand (RANKL) and osteoprotegerin regulation and partial rescue of osteoclastogenesis in Runx2-/- mice by RANKL transgene.
Enomoto H, Shiojiri S, Hoshi K, Furuichi T, Fukuyama R, Yoshida CA, Kanatani N, Nakamura R, Mizuno A, Zanma A, Yano K, Yasuda H, Higashio K, Takada K, Komori T. Enomoto H, et al. Among authors: kanatani n. J Biol Chem. 2003 Jun 27;278(26):23971-7. doi: 10.1074/jbc.M302457200. Epub 2003 Apr 15. J Biol Chem. 2003. PMID: 12697767 Free article.
Runx2 determines bone maturity and turnover rate in postnatal bone development and is involved in bone loss in estrogen deficiency.
Maruyama Z, Yoshida CA, Furuichi T, Amizuka N, Ito M, Fukuyama R, Miyazaki T, Kitaura H, Nakamura K, Fujita T, Kanatani N, Moriishi T, Yamana K, Liu W, Kawaguchi H, Nakamura K, Komori T. Maruyama Z, et al. Among authors: kanatani n. Dev Dyn. 2007 Jul;236(7):1876-90. doi: 10.1002/dvdy.21187. Dev Dyn. 2007. PMID: 17497678 Free article.
Akt regulates skeletal development through GSK3, mTOR, and FoxOs.
Rokutanda S, Fujita T, Kanatani N, Yoshida CA, Komori H, Liu W, Mizuno A, Komori T. Rokutanda S, et al. Among authors: kanatani n. Dev Biol. 2009 Apr 1;328(1):78-93. doi: 10.1016/j.ydbio.2009.01.009. Epub 2009 Jan 14. Dev Biol. 2009. PMID: 19389373 Free article.
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