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SARS-CoV-2 disrupts respiratory vascular barriers by suppressing Claudin-5 expression.
Hashimoto R, Takahashi J, Shirakura K, Funatsu R, Kosugi K, Deguchi S, Yamamoto M, Tsunoda Y, Morita M, Muraoka K, Tanaka M, Kanbara T, Tanaka S, Tamiya S, Tokunoh N, Kawai A, Ikawa M, Ono C, Tachibana K, Kondoh M, Obana M, Matsuura Y, Ohsumi A, Noda T, Yamamoto T, Yoshioka Y, Torisawa YS, Date H, Fujio Y, Nagao M, Takayama K, Okada Y. Hashimoto R, et al. Among authors: kosugi k. Sci Adv. 2022 Sep 23;8(38):eabo6783. doi: 10.1126/sciadv.abo6783. Epub 2022 Sep 21. Sci Adv. 2022. PMID: 36129989 Free PMC article.
Elucidation of the liver pathophysiology of COVID-19 patients using liver-on-a-chips.
Deguchi S, Kosugi K, Hashimoto R, Sakamoto A, Yamamoto M, Krol RP, Gee P, Negoro R, Noda T, Yamamoto T, Torisawa YS, Nagao M, Takayama K. Deguchi S, et al. Among authors: kosugi k. PNAS Nexus. 2023 Mar 7;2(3):pgad029. doi: 10.1093/pnasnexus/pgad029. eCollection 2023 Mar. PNAS Nexus. 2023. PMID: 36896132 Free PMC article.
Generation of Tetrafluoroethylene-Propylene Elastomer-Based Microfluidic Devices for Drug Toxicity and Metabolism Studies.
Sano E, Deguchi S, Matsuoka N, Tsuda M, Wang M, Kosugi K, Mori C, Yagi K, Wada A, Yamasaki S, Kawai T, Yodogawa M, Mizuguchi H, Nakazawa N, Yamashita F, Torisawa YS, Takayama K. Sano E, et al. Among authors: kosugi k. ACS Omega. 2021 Sep 15;6(38):24859-24865. doi: 10.1021/acsomega.1c03719. eCollection 2021 Sep 28. ACS Omega. 2021. PMID: 34604667 Free PMC article.