Karar J - Search Results

1

Modulating the tumor microenvironment to increase radiation responsiveness.

Karar J, Maity A. Karar J, et al. Cancer Biol Ther. 2009 Nov;8(21):1994-2001. doi: 10.4161/cbt.8.21.9988. Epub 2009 Nov 3. Cancer Biol Ther. 2009. PMID: 19823031 Free PMC article. Review.

2

Dual PI3K/mTOR inhibitor NVP-BEZ235 suppresses hypoxia-inducible factor (HIF)-1α expression by blocking protein translation and increases cell death under hypoxia.

Karar J, Cerniglia GJ, Lindsten T, Koumenis C, Maity A. Karar J, et al. Cancer Biol Ther. 2012 Sep;13(11):1102-11. doi: 10.4161/cbt.21144. Epub 2012 Aug 16. Cancer Biol Ther. 2012. PMID: 22895065 Free PMC article.

3

Inhibition of autophagy as a strategy to augment radiosensitization by the dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235.

Cerniglia GJ, Karar J, Tyagi S, Christofidou-Solomidou M, Rengan R, Koumenis C, Maity A. Cerniglia GJ, et al. Among authors: karar j. Mol Pharmacol. 2012 Dec;82(6):1230-40. doi: 10.1124/mol.112.080408. Epub 2012 Sep 18. Mol Pharmacol. 2012. PMID: 22989521 Free PMC article.

4

In vivo profiling of hypoxic gene expression in gliomas using the hypoxia marker EF5 and laser-capture microdissection.

Marotta D, Karar J, Jenkins WT, Kumanova M, Jenkins KW, Tobias JW, Baldwin D, Hatzigeorgiou A, Alexiou P, Evans SM, Alarcon R, Maity A, Koch C, Koumenis C. Marotta D, et al. Among authors: karar j. Cancer Res. 2011 Feb 1;71(3):779-89. doi: 10.1158/0008-5472.CAN-10-3061. Epub 2011 Jan 25. Cancer Res. 2011. PMID: 21266355 Free PMC article.

5

PI3K/AKT/mTOR Pathway in Angiogenesis.

Karar J, Maity A. Karar J, et al. Front Mol Neurosci. 2011 Dec 2;4:51. doi: 10.3389/fnmol.2011.00051. eCollection 2011. Front Mol Neurosci. 2011. PMID: 22144946 Free PMC article.

6

LIMD2 is a small LIM-only protein overexpressed in metastatic lesions that regulates cell motility and tumor progression by directly binding to and activating the integrin-linked kinase.

Peng H, Talebzadeh-Farrooji M, Osborne MJ, Prokop JW, McDonald PC, Karar J, Hou Z, He M, Kebebew E, Orntoft T, Herlyn M, Caton AJ, Fredericks W, Malkowicz B, Paterno CS, Carolin AS, Speicher DW, Skordalakes E, Huang Q, Dedhar S, Borden KLB, Rauscher FJ 3rd. Peng H, et al. Among authors: karar j. Cancer Res. 2014 Mar 1;74(5):1390-1403. doi: 10.1158/0008-5472.CAN-13-1275. Cancer Res. 2014. PMID: 24590809 Free PMC article.

7

Anti-tumorigenic effects of Type 1 interferon are subdued by integrated stress responses.

Bhattacharya S, HuangFu WC, Dong G, Qian J, Baker DP, Karar J, Koumenis C, Diehl JA, Fuchs SY. Bhattacharya S, et al. Among authors: karar j. Oncogene. 2013 Sep 5;32(36):4214-21. doi: 10.1038/onc.2012.439. Epub 2012 Oct 8. Oncogene. 2013. PMID: 23045272 Free PMC article.

8

Germline mutation of Bap1 accelerates development of asbestos-induced malignant mesothelioma.

Xu J, Kadariya Y, Cheung M, Pei J, Talarchek J, Sementino E, Tan Y, Menges CW, Cai KQ, Litwin S, Peng H, Karar J, Rauscher FJ, Testa JR. Xu J, et al. Among authors: karar j. Cancer Res. 2014 Aug 15;74(16):4388-97. doi: 10.1158/0008-5472.CAN-14-1328. Epub 2014 Jun 13. Cancer Res. 2014. PMID: 24928783 Free PMC article.

9

Familial and Somatic BAP1 Mutations Inactivate ASXL1/2-Mediated Allosteric Regulation of BAP1 Deubiquitinase by Targeting Multiple Independent Domains.

Peng H, Prokop J, Karar J, Park K, Cao L, Harbour JW, Bowcock AM, Malkowicz SB, Cheung M, Testa JR, Rauscher FJ 3rd. Peng H, et al. Among authors: karar j. Cancer Res. 2018 Mar 1;78(5):1200-1213. doi: 10.1158/0008-5472.CAN-17-2876. Epub 2017 Dec 28. Cancer Res. 2018. PMID: 29284740 Free PMC article.

10

Structure and specificity of the bacterial cysteine methyltransferase effector NleE suggests a novel substrate in human DNA repair pathway.

Yao Q, Zhang L, Wan X, Chen J, Hu L, Ding X, Li L, Karar J, Peng H, Chen S, Huang N, Rauscher FJ 3rd, Shao F. Yao Q, et al. Among authors: karar j. PLoS Pathog. 2014 Nov 20;10(11):e1004522. doi: 10.1371/journal.ppat.1004522. eCollection 2014 Nov. PLoS Pathog. 2014. PMID: 25412445 Free PMC article.

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