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Nucleoside-modified VEGFC mRNA induces organ-specific lymphatic growth and reverses experimental lymphedema.
Szőke D, Kovács G, Kemecsei É, Bálint L, Szoták-Ajtay K, Aradi P, Styevkóné Dinnyés A, Mui BL, Tam YK, Madden TD, Karikó K, Kataru RP, Hope MJ, Weissman D, Mehrara BJ, Pardi N, Jakus Z. Szőke D, et al. Among authors: kariko k. Nat Commun. 2021 Jun 8;12(1):3460. doi: 10.1038/s41467-021-23546-6. Nat Commun. 2021. PMID: 34103491 Free PMC article.
mRNA is an endogenous ligand for Toll-like receptor 3.
Karikó K, Ni H, Capodici J, Lamphier M, Weissman D. Karikó K, et al. J Biol Chem. 2004 Mar 26;279(13):12542-50. doi: 10.1074/jbc.M310175200. Epub 2004 Jan 16. J Biol Chem. 2004. PMID: 14729660 Free article.
102 results