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The CXCR4/CXCR7/SDF-1 pathway contributes to the pathogenesis of Shiga toxin-associated hemolytic uremic syndrome in humans and mice.
Petruzziello-Pellegrini TN, Yuen DA, Page AV, Patel S, Soltyk AM, Matouk CC, Wong DK, Turgeon PJ, Fish JE, Ho JJ, Steer BM, Khajoee V, Tigdi J, Lee WL, Motto DG, Advani A, Gilbert RE, Karumanchi SA, Robinson LA, Tarr PI, Liles WC, Brunton JL, Marsden PA. Petruzziello-Pellegrini TN, et al. Among authors: karumanchi sa. J Clin Invest. 2012 Feb;122(2):759-76. doi: 10.1172/JCI57313. Epub 2012 Jan 9. J Clin Invest. 2012. PMID: 22232208 Free PMC article.
Placental senescence pathophysiology is shared between peripartum cardiomyopathy and preeclampsia in mouse and human.
Roh JD, Castro C, Yu A, Rana S, Shahul S, Gray KJ, Honigberg MC, Ricke-Hoch M, Iwamoto Y, Yeri A, Kitchen R, Guerra JB, Hobson R, Chaudhari V, Chang B, Sarma A, Lerchenmüller C, Al Sayed ZR, Diaz Verdugo C, Xia P, Skarbianskis N, Zeisel A, Bauersachs J, Kirkland JL, Karumanchi SA, Gorcsan J 3rd, Sugahara M, Damp J, Hanley-Yanez K, Ellinor PT, Arany Z, McNamara DM; IPAC Investigators; Hilfiker-Kleiner D, Rosenzweig A. Roh JD, et al. Among authors: karumanchi sa. Sci Transl Med. 2024 Apr 17;16(743):eadi0077. doi: 10.1126/scitranslmed.adi0077. Epub 2024 Apr 17. Sci Transl Med. 2024. PMID: 38630848
High-throughput mRNA sequencing of human placenta shows sex differences across gestation.
Flowers AE, Gonzalez TL, Wang Y, Santiskulvong C, Clark EL, Novoa A, Jefferies CA, Lawrenson K, Chan JL, Joshi NV, Zhu Y, Tseng HR, Wang ET, Ishimori M, Karumanchi SA, Williams J 3rd, Pisarska MD. Flowers AE, et al. Among authors: karumanchi sa. Placenta. 2024 May;150:8-21. doi: 10.1016/j.placenta.2024.03.005. Epub 2024 Mar 21. Placenta. 2024. PMID: 38537412
SOX9 switch links regeneration to fibrosis at the single-cell level in mammalian kidneys.
Aggarwal S, Wang Z, Rincon Fernandez Pacheco D, Rinaldi A, Rajewski A, Callemeyn J, Van Loon E, Lamarthée B, Covarrubias AE, Hou J, Yamashita M, Akiyama H, Karumanchi SA, Svendsen CN, Noble PW, Jordan SC, Breunig JJ, Naesens M, Cippà PE, Kumar S. Aggarwal S, et al. Among authors: karumanchi sa. Science. 2024 Feb 23;383(6685):eadd6371. doi: 10.1126/science.add6371. Epub 2024 Feb 23. Science. 2024. PMID: 38386758
Serial placental growth factor-based testing in pre-eclampsia.
Cerdeira AS, Karumanchi SA. Cerdeira AS, et al. Among authors: karumanchi sa. Lancet. 2024 Feb 17;403(10427):588-589. doi: 10.1016/S0140-6736(23)02578-3. Epub 2024 Feb 8. Lancet. 2024. PMID: 38342125 No abstract available.
354 results