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A Translational Pharmacology Approach to Predicting Outcomes of Preexposure Prophylaxis Against HIV in Men and Women Using Tenofovir Disoproxil Fumarate With or Without Emtricitabine.
Cottrell ML, Yang KH, Prince HM, Sykes C, White N, Malone S, Dellon ES, Madanick RD, Shaheen NJ, Hudgens MG, Wulff J, Patterson KB, Nelson JA, Kashuba AD. Cottrell ML, et al. Among authors: kashuba ad. J Infect Dis. 2016 Jul 1;214(1):55-64. doi: 10.1093/infdis/jiw077. Epub 2016 Feb 24. J Infect Dis. 2016. PMID: 26917574 Free PMC article. Clinical Trial.
Lopinavir/ritonavir induces the hepatic activity of cytochrome P450 enzymes CYP2C9, CYP2C19, and CYP1A2 but inhibits the hepatic and intestinal activity of CYP3A as measured by a phenotyping drug cocktail in healthy volunteers.
Yeh RF, Gaver VE, Patterson KB, Rezk NL, Baxter-Meheux F, Blake MJ, Eron JJ Jr, Klein CE, Rublein JC, Kashuba AD. Yeh RF, et al. Among authors: kashuba ad. J Acquir Immune Defic Syndr. 2006 May;42(1):52-60. doi: 10.1097/01.qai.0000219774.20174.64. J Acquir Immune Defic Syndr. 2006. PMID: 16639344
The pharmacokinetics and viral activity of tenofovir in the male genital tract.
Vourvahis M, Tappouni HL, Patterson KB, Chen YC, Rezk NL, Fiscus SA, Kearney BP, Rooney JF, Hui J, Cohen MS, Kashuba AD. Vourvahis M, et al. Among authors: kashuba ad. J Acquir Immune Defic Syndr. 2008 Mar 1;47(3):329-33. doi: 10.1097/QAI.0b013e3181632cc3. J Acquir Immune Defic Syndr. 2008. PMID: 18197124 Free PMC article. Clinical Trial.
Studies on antiretroviral drug concentrations in breast milk: validation of a liquid chromatography-tandem mass spectrometric method for the determination of 7 anti-human immunodeficiency virus medications.
Rezk NL, White N, Bridges AS, Abdel-Megeed MF, Mohamed TM, Moselhy SS, Kashuba AD. Rezk NL, et al. Among authors: kashuba ad. Ther Drug Monit. 2008 Oct;30(5):611-9. doi: 10.1097/FTD.0b013e318186e08e. Ther Drug Monit. 2008. PMID: 18758393 Free PMC article. Clinical Trial.
275 results