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Cancer cell-intrinsic expression of MHC II in lung cancer cell lines is actively restricted by MEK/ERK signaling and epigenetic mechanisms.
J Immunother Cancer. 2020 Apr;8(1):e000441. doi: 10.1136/jitc-2019-000441.
J Immunother Cancer. 2020.
PMID: 32312906
Free PMC article.
Tumor-intrinsic response to IFNγ shapes the tumor microenvironment and anti-PD-1 response in NSCLC.
Bullock BL, Kimball AK, Poczobutt JM, Neuwelt AJ, Li HY, Johnson AM, Kwak JW, Kleczko EK, Kaspar RE, Wagner EK, Hopp K, Schenk EL, Weiser-Evans MC, Clambey ET, Nemenoff RA.
Bullock BL, et al. Among authors: kaspar re.
Life Sci Alliance. 2019 May 27;2(3):e201900328. doi: 10.26508/lsa.201900328. Print 2019 Jun.
Life Sci Alliance. 2019.
PMID: 31133614
Free PMC article.
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Cancer Cell-Intrinsic Expression of MHC Class II Regulates the Immune Microenvironment and Response to Anti-PD-1 Therapy in Lung Adenocarcinoma.
Johnson AM, Bullock BL, Neuwelt AJ, Poczobutt JM, Kaspar RE, Li HY, Kwak JW, Hopp K, Weiser-Evans MCM, Heasley LE, Schenk EL, Clambey ET, Nemenoff RA.
Johnson AM, et al. Among authors: kaspar re.
J Immunol. 2020 Apr 15;204(8):2295-2307. doi: 10.4049/jimmunol.1900778. Epub 2020 Mar 16.
J Immunol. 2020.
PMID: 32179637
Free PMC article.
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High-Dimensional Characterization of IL-10 Production and IL-10-Dependent Regulation during Primary Gammaherpesvirus Infection.
Kimball AK, Oko LM, Kaspar RE, van Dyk LF, Clambey ET.
Kimball AK, et al. Among authors: kaspar re.
Immunohorizons. 2019 Mar 21;3(3):94-109. doi: 10.4049/immunohorizons.1800088.
Immunohorizons. 2019.
PMID: 31356152
Free article.
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Multidimensional analysis of Gammaherpesvirus RNA expression reveals unexpected heterogeneity of gene expression.
Oko LM, Kimball AK, Kaspar RE, Knox AN, Coleman CB, Rochford R, Chang T, Alderete B, van Dyk LF, Clambey ET.
Oko LM, et al. Among authors: kaspar re.
PLoS Pathog. 2019 Jun 5;15(6):e1007849. doi: 10.1371/journal.ppat.1007849. eCollection 2019 Jun.
PLoS Pathog. 2019.
PMID: 31166996
Free PMC article.
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Receptor for hyaluronan-mediated motility (RHAMM) defines an invasive niche associated with tumor progression and predicts poor outcomes in breast cancer patients.
Tarullo SE, He Y, Daughters C, Knutson TP, Henzler CM, Price MA, Shanley R, Witschen P, Tolg C, Kaspar RE, Hallstrom C, Gittsovich L, Sulciner ML, Zhang X, Forster CL, Lange CA, Shats O, Desler M, Cowan KH, Yee D, Schwertfeger KL, Turley EA, McCarthy JB, Nelson AC.
Tarullo SE, et al. Among authors: kaspar re.
J Pathol. 2023 Jul;260(3):289-303. doi: 10.1002/path.6082. Epub 2023 Apr 26.
J Pathol. 2023.
PMID: 37186300
Free PMC article.
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