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Proteomic analysis of circulating immune cells identifies cellular phenotypes associated with COVID-19 severity.
Potts M, Fletcher-Etherington A, Nightingale K, Mescia F, Bergamaschi L, Calero-Nieto FJ, Antrobus R, Williamson J; Cambridge Institute of Therapeutic Immunology and Infectious Disease-National Institute of Health Research (CITIID-NIHR) COVID BioResource Collaboration; Parsons H, Huttlin EL, Kingston N, Göttgens B, Bradley JR, Lehner PJ, Matheson NJ, Smith KGC, Wills MR, Lyons PA, Weekes MP. Potts M, et al. Among authors: nightingale k. Cell Rep. 2023 Jun 27;42(6):112613. doi: 10.1016/j.celrep.2023.112613. Epub 2023 May 29. Cell Rep. 2023. PMID: 37302069 Free PMC article.
Human cytomegalovirus degrades DMXL1 to inhibit autophagy, lysosomal acidification, and viral assembly.
Li H, Fletcher-Etherington A, Hunter LM, Keshri S, Fielding CA, Nightingale K, Ravenhill B, Nobre L, Potts M, Antrobus R, Crump CM, Rubinsztein DC, Stanton RJ, Weekes MP. Li H, et al. Among authors: nightingale k. Cell Host Microbe. 2024 Apr 10;32(4):466-478.e11. doi: 10.1016/j.chom.2024.02.013. Epub 2024 Mar 12. Cell Host Microbe. 2024. PMID: 38479395 Free article.
ADAM17 targeting by human cytomegalovirus remodels the cell surface proteome to simultaneously regulate multiple immune pathways.
Rubina A, Patel M, Nightingale K, Potts M, Fielding CA, Kollnberger S, Lau B, Ladell K, Miners KL, Nichols J, Nobre L, Roberts D, Trinca TM, Twohig JP, Vlahava VM, Davison AJ, Price DA, Tomasec P, Wilkinson GWG, Weekes MP, Stanton RJ, Wang ECY. Rubina A, et al. Among authors: nightingale k. Proc Natl Acad Sci U S A. 2023 Aug 15;120(33):e2303155120. doi: 10.1073/pnas.2303155120. Epub 2023 Aug 10. Proc Natl Acad Sci U S A. 2023. PMID: 37561786 Free PMC article.
Regulation of Ov2 by virus encoded microRNAs.
Nightingale K, Dry I, Hopkins J, Dalziel R. Nightingale K, et al. Vet Res Commun. 2019 May;43(2):99-104. doi: 10.1007/s11259-019-09749-9. Epub 2019 Mar 19. Vet Res Commun. 2019. PMID: 30888610 Free PMC article.
Strain-Dependent Restriction of Human Cytomegalovirus by Zinc Finger Antiviral Proteins.
Lista MJ, Witney AA, Nichols J, Davison AJ, Wilson H, Latham KA, Ravenhill BJ, Nightingale K, Stanton RJ, Weekes MP, Neil SJD, Swanson CM, Strang BL. Lista MJ, et al. Among authors: nightingale k. J Virol. 2023 Mar 30;97(3):e0184622. doi: 10.1128/jvi.01846-22. Epub 2023 Mar 14. J Virol. 2023. PMID: 36916924 Free PMC article.
Human cytomegalovirus protein pUL36: A dual cell death pathway inhibitor.
Fletcher-Etherington A, Nobre L, Nightingale K, Antrobus R, Nichols J, Davison AJ, Stanton RJ, Weekes MP. Fletcher-Etherington A, et al. Among authors: nightingale k. Proc Natl Acad Sci U S A. 2020 Aug 4;117(31):18771-18779. doi: 10.1073/pnas.2001887117. Epub 2020 Jul 20. Proc Natl Acad Sci U S A. 2020. PMID: 32690704 Free PMC article.
Human cytomegalovirus protein RL1 degrades the antiviral factor SLFN11 via recruitment of the CRL4 E3 ubiquitin ligase complex.
Nightingale K, Potts M, Hunter LM, Fielding CA, Zerbe CM, Fletcher-Etherington A, Nobre L, Wang ECY, Strang BL, Houghton JW, Antrobus R, Suarez NM, Nichols J, Davison AJ, Stanton RJ, Weekes MP. Nightingale K, et al. Proc Natl Acad Sci U S A. 2022 Feb 8;119(6):e2108173119. doi: 10.1073/pnas.2108173119. Proc Natl Acad Sci U S A. 2022. PMID: 35105802 Free PMC article.
Ov2 is a modulator of OvHV-2 RTA mediated gene expression.
Dry I, Nightingale K, Ferguson J, Hopkins J, Dalziel R. Dry I, et al. Among authors: nightingale k. Vet Res Commun. 2019 May;43(2):91-97. doi: 10.1007/s11259-019-09748-w. Epub 2019 Mar 21. Vet Res Commun. 2019. PMID: 30900113 Free PMC article.
Suppression of costimulation by human cytomegalovirus promotes evasion of cellular immune defenses.
Wang ECY, Pjechova M, Nightingale K, Vlahava VM, Patel M, Ruckova E, Forbes SK, Nobre L, Antrobus R, Roberts D, Fielding CA, Seirafian S, Davies J, Murrell I, Lau B, Wilkie GS, Suárez NM, Stanton RJ, Vojtesek B, Davison A, Lehner PJ, Weekes MP, Wilkinson GWG, Tomasec P. Wang ECY, et al. Among authors: nightingale k. Proc Natl Acad Sci U S A. 2018 May 8;115(19):4998-5003. doi: 10.1073/pnas.1720950115. Epub 2018 Apr 24. Proc Natl Acad Sci U S A. 2018. PMID: 29691324 Free PMC article.
15 results