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HDAC1 links early life stress to schizophrenia-like phenotypes.
Bahari-Javan S, Varbanov H, Halder R, Benito E, Kaurani L, Burkhardt S, Anderson-Schmidt H, Anghelescu I, Budde M, Stilling RM, Costa J, Medina J, Dietrich DE, Figge C, Folkerts H, Gade K, Heilbronner U, Koller M, Konrad C, Nussbeck SY, Scherk H, Spitzer C, Stierl S, Stöckel J, Thiel A, von Hagen M, Zimmermann J, Zitzelsberger A, Schulz S, Schmitt A, Delalle I, Falkai P, Schulze TG, Dityatev A, Sananbenesi F, Fischer A. Bahari-Javan S, et al. Among authors: kaurani l. Proc Natl Acad Sci U S A. 2017 Jun 6;114(23):E4686-E4694. doi: 10.1073/pnas.1613842114. Epub 2017 May 22. Proc Natl Acad Sci U S A. 2017. PMID: 28533418 Free PMC article.
KMT2A and KMT2B Mediate Memory Function by Affecting Distinct Genomic Regions.
Kerimoglu C, Sakib MS, Jain G, Benito E, Burkhardt S, Capece V, Kaurani L, Halder R, Agís-Balboa RC, Stilling R, Urbanke H, Kranz A, Stewart AF, Fischer A. Kerimoglu C, et al. Among authors: kaurani l. Cell Rep. 2017 Jul 18;20(3):538-548. doi: 10.1016/j.celrep.2017.06.072. Cell Rep. 2017. PMID: 28723559 Free article.
The diphenylpyrazole compound anle138b blocks Aβ channels and rescues disease phenotypes in a mouse model for amyloid pathology.
Martinez Hernandez A, Urbanke H, Gillman AL, Lee J, Ryazanov S, Agbemenyah HY, Benito E, Jain G, Kaurani L, Grigorian G, Leonov A, Rezaei-Ghaleh N, Wilken P, Arce FT, Wagner J, Fuhrmann M, Caruana M, Camilleri A, Vassallo N, Zweckstetter M, Benz R, Giese A, Schneider A, Korte M, Lal R, Griesinger C, Eichele G, Fischer A. Martinez Hernandez A, et al. Among authors: kaurani l. EMBO Mol Med. 2018 Jan;10(1):32-47. doi: 10.15252/emmm.201707825. EMBO Mol Med. 2018. PMID: 29208638 Free PMC article.
Childhood Trauma in Schizophrenia: Current Findings and Research Perspectives.
Popovic D, Schmitt A, Kaurani L, Senner F, Papiol S, Malchow B, Fischer A, Schulze TG, Koutsouleris N, Falkai P. Popovic D, et al. Among authors: kaurani l. Front Neurosci. 2019 Mar 21;13:274. doi: 10.3389/fnins.2019.00274. eCollection 2019. Front Neurosci. 2019. PMID: 30983960 Free PMC article. Review.
A combined miRNA-piRNA signature to detect Alzheimer's disease.
Jain G, Stuendl A, Rao P, Berulava T, Pena Centeno T, Kaurani L, Burkhardt S, Delalle I, Kornhuber J, Hüll M, Maier W, Peters O, Esselmann H, Schulte C, Deuschle C, Synofzik M, Wiltfang J, Mollenhauer B, Maetzler W, Schneider A, Fischer A. Jain G, et al. Among authors: kaurani l. Transl Psychiatry. 2019 Oct 7;9(1):250. doi: 10.1038/s41398-019-0579-2. Transl Psychiatry. 2019. PMID: 31591382 Free PMC article.
A microRNA signature that correlates with cognition and is a target against cognitive decline.
Islam MR, Kaurani L, Berulava T, Heilbronner U, Budde M, Centeno TP, Elerdashvili V, Zafieriou MP, Benito E, Sertel SM, Goldberg M, Senner F, Kalman JL, Burkhardt S, Oepen AS, Sakib MS, Kerimoglu C, Wirths O, Bickeböller H, Bartels C, Brosseron F, Buerger K, Cosma NC, Fliessbach K, Heneka MT, Janowitz D, Kilimann I, Kleinedam L, Laske C, Metzger CD, Munk MH, Perneczky R, Peters O, Priller J, Rauchmann BS, Roy N, Schneider A, Spottke A, Spruth EJ, Teipel S, Tscheuschler M, Wagner M, Wiltfang J, Düzel E, Jessen F; Delcode Study Group; Rizzoli SO, Zimmermann WH, Schulze TG, Falkai P, Sananbenesi F, Fischer A. Islam MR, et al. Among authors: kaurani l. EMBO Mol Med. 2021 Nov 8;13(11):e13659. doi: 10.15252/emmm.202013659. Epub 2021 Oct 11. EMBO Mol Med. 2021. PMID: 34633146 Free PMC article.
Conserved reduction of m6A RNA modifications during aging and neurodegeneration is linked to changes in synaptic transcripts.
Castro-Hernández R, Berulava T, Metelova M, Epple R, Peña Centeno T, Richter J, Kaurani L, Pradhan R, Sakib MS, Burkhardt S, Ninov M, Bohnsack KE, Bohnsack MT, Delalle I, Fischer A. Castro-Hernández R, et al. Among authors: kaurani l. Proc Natl Acad Sci U S A. 2023 Feb 28;120(9):e2204933120. doi: 10.1073/pnas.2204933120. Epub 2023 Feb 22. Proc Natl Acad Sci U S A. 2023. PMID: 36812208 Free PMC article.
Association of early life stress and cognitive performance in patients with schizophrenia and healthy controls.
Senner F, Schneider-Axmann T, Kaurani L, Zimmermann J, Wiltfang J, von Hagen M, Vogl T, Spitzer C, Senner S, Schulte EC, Schmauß M, Schaupp SK, Reimer J, Reich-Erkelenz D, Papiol S, Kohshour MO, Lang FU, Konrad C, Kirchner SK, Kalman JL, Juckel G, Heilbronner M, Heilbronner U, Figge C, Eyl RE, Dietrich D, Budde M, Angelescu IG, Adorjan K, Schmitt A, Fischer A, Falkai P, Schulze TG. Senner F, et al. Among authors: kaurani l. Schizophr Res Cogn. 2023 Feb 11;32:100280. doi: 10.1016/j.scog.2023.100280. eCollection 2023 Jun. Schizophr Res Cogn. 2023. PMID: 36846489 Free PMC article.
Postnatal expression of the lysine methyltransferase SETD1B is essential for learning and the regulation of neuron-enriched genes.
Michurina A, Sakib MS, Kerimoglu C, Krüger DM, Kaurani L, Islam MR, Joshi PD, Schröder S, Centeno TP, Zhou J, Pradhan R, Cha J, Xu X, Eichele G, Zeisberg EM, Kranz A, Stewart AF, Fischer A. Michurina A, et al. Among authors: kaurani l. EMBO J. 2022 Jan 4;41(1):e106459. doi: 10.15252/embj.2020106459. Epub 2021 Nov 22. EMBO J. 2022. PMID: 34806773 Free PMC article.
24 results