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Page 1
METTL6 is a tRNA m3C methyltransferase that regulates pluripotency and tumor cell growth.
Sci Adv. 2020 Aug 26;6(35):eaaz4551. doi: 10.1126/sciadv.aaz4551. eCollection 2020 Aug.
Sci Adv. 2020.
PMID: 32923617
Free PMC article.
Novel genomic island modifies DNA with 7-deazaguanine derivatives.
Thiaville JJ, Kellner SM, Yuan Y, Hutinet G, Thiaville PC, Jumpathong W, Mohapatra S, Brochier-Armanet C, Letarov AV, Hillebrand R, Malik CK, Rizzo CJ, Dedon PC, de Crécy-Lagard V.
Thiaville JJ, et al. Among authors: kellner sm.
Proc Natl Acad Sci U S A. 2016 Mar 15;113(11):E1452-9. doi: 10.1073/pnas.1518570113. Epub 2016 Feb 29.
Proc Natl Acad Sci U S A. 2016.
PMID: 26929322
Free PMC article.
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The rRNA m6A methyltransferase METTL5 is involved in pluripotency and developmental programs.
Ignatova VV, Stolz P, Kaiser S, Gustafsson TH, Lastres PR, Sanz-Moreno A, Cho YL, Amarie OV, Aguilar-Pimentel A, Klein-Rodewald T, Calzada-Wack J, Becker L, Marschall S, Kraiger M, Garrett L, Seisenberger C, Hölter SM, Borland K, Van De Logt E, Jansen PWTC, Baltissen MP, Valenta M, Vermeulen M, Wurst W, Gailus-Durner V, Fuchs H, Hrabe de Angelis M, Rando OJ, Kellner SM, Bultmann S, Schneider R.
Ignatova VV, et al. Among authors: kellner sm.
Genes Dev. 2020 May 1;34(9-10):715-729. doi: 10.1101/gad.333369.119. Epub 2020 Mar 26.
Genes Dev. 2020.
PMID: 32217665
Free PMC article.
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Identification and rescue of a tRNA wobble inosine deficiency causing intellectual disability disorder.
Ramos J, Proven M, Halvardson J, Hagelskamp F, Kuchinskaya E, Phelan B, Bell R, Kellner SM, Feuk L, Thuresson AC, Fu D.
Ramos J, et al. Among authors: kellner sm.
RNA. 2020 Nov;26(11):1654-1666. doi: 10.1261/rna.076380.120. Epub 2020 Aug 6.
RNA. 2020.
PMID: 32763916
Free PMC article.
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Formation of tRNA Wobble Inosine in Humans Is Disrupted by a Millennia-Old Mutation Causing Intellectual Disability.
Ramos J, Han L, Li Y, Hagelskamp F, Kellner SM, Alkuraya FS, Phizicky EM, Fu D.
Ramos J, et al. Among authors: kellner sm.
Mol Cell Biol. 2019 Sep 11;39(19):e00203-19. doi: 10.1128/MCB.00203-19. Print 2019 Oct 1.
Mol Cell Biol. 2019.
PMID: 31263000
Free PMC article.
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TRMT1-Catalyzed tRNA Modifications Are Required for Redox Homeostasis To Ensure Proper Cellular Proliferation and Oxidative Stress Survival.
Dewe JM, Fuller BL, Lentini JM, Kellner SM, Fu D.
Dewe JM, et al. Among authors: kellner sm.
Mol Cell Biol. 2017 Oct 13;37(21):e00214-17. doi: 10.1128/MCB.00214-17. Print 2017 Nov 1.
Mol Cell Biol. 2017.
PMID: 28784718
Free PMC article.
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An extensive allelic series of Drosophila kae1 mutants reveals diverse and tissue-specific requirements for t6A biogenesis.
Lin CJ, Smibert P, Zhao X, Hu JF, Ramroop J, Kellner SM, Benton MA, Govind S, Dedon PC, Sternglanz R, Lai EC.
Lin CJ, et al. Among authors: kellner sm.
RNA. 2015 Dec;21(12):2103-18. doi: 10.1261/rna.053934.115. Epub 2015 Oct 29.
RNA. 2015.
PMID: 26516084
Free PMC article.
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