Kelly EJ - Search Results

1

Predicting tubular reabsorption with a human kidney proximal tubule tissue-on-a-chip and physiologically-based modeling.

Sakolish C, Chen Z, Dalaijamts C, Mitra K, Liu Y, Fulton T, Wade TL, Kelly EJ, Rusyn I, Chiu WA. Sakolish C, et al. Among authors: kelly ej. Toxicol In Vitro. 2020 Mar;63:104752. doi: 10.1016/j.tiv.2019.104752. Epub 2019 Dec 17. Toxicol In Vitro. 2020. PMID: 31857146 Free PMC article.

2

Development of a microphysiological model of human kidney proximal tubule function.

Weber EJ, Chapron A, Chapron BD, Voellinger JL, Lidberg KA, Yeung CK, Wang Z, Yamaura Y, Hailey DW, Neumann T, Shen DD, Thummel KE, Muczynski KA, Himmelfarb J, Kelly EJ. Weber EJ, et al. Among authors: kelly ej. Kidney Int. 2016 Sep;90(3):627-37. doi: 10.1016/j.kint.2016.06.011. Kidney Int. 2016. PMID: 27521113 Free PMC article.

3

Characterization of rat or human hepatocytes cultured in microphysiological systems (MPS) to identify hepatotoxicity.

Chang SY, Voellinger JL, Van Ness KP, Chapron B, Shaffer RM, Neumann T, White CC, Kavanagh TJ, Kelly EJ, Eaton DL. Chang SY, et al. Among authors: kelly ej. Toxicol In Vitro. 2017 Apr;40:170-183. doi: 10.1016/j.tiv.2017.01.007. Epub 2017 Jan 13. Toxicol In Vitro. 2017. PMID: 28089783

4

Technology Transfer of the Microphysiological Systems: A Case Study of the Human Proximal Tubule Tissue Chip.

Sakolish C, Weber EJ, Kelly EJ, Himmelfarb J, Mouneimne R, Grimm FA, House JS, Wade T, Han A, Chiu WA, Rusyn I. Sakolish C, et al. Among authors: kelly ej. Sci Rep. 2018 Oct 5;8(1):14882. doi: 10.1038/s41598-018-33099-2. Sci Rep. 2018. PMID: 30291268 Free PMC article.

5

Translational Assessment of Drug-Induced Proximal Tubule Injury Using a Kidney Microphysiological System.

Maass C, Sorensen NB, Himmelfarb J, Kelly EJ, Stokes CL, Cirit M. Maass C, et al. Among authors: kelly ej. CPT Pharmacometrics Syst Pharmacol. 2019 May;8(5):316-325. doi: 10.1002/psp4.12400. Epub 2019 Apr 9. CPT Pharmacometrics Syst Pharmacol. 2019. PMID: 30869201 Free PMC article.

6

Microphysiological system modeling of ochratoxin A-associated nephrotoxicity.

Imaoka T, Yang J, Wang L, McDonald MG, Afsharinejad Z, Bammler TK, Van Ness K, Yeung CK, Rettie AE, Himmelfarb J, Kelly EJ. Imaoka T, et al. Among authors: kelly ej. Toxicology. 2020 Nov;444:152582. doi: 10.1016/j.tox.2020.152582. Epub 2020 Sep 6. Toxicology. 2020. PMID: 32905824 Free PMC article.

7

Bridging the gap between in silico and in vivo by modeling opioid disposition in a kidney proximal tubule microphysiological system.

Imaoka T, Huang W, Shum S, Hailey DW, Chang SY, Chapron A, Yeung CK, Himmelfarb J, Isoherranen N, Kelly EJ. Imaoka T, et al. Among authors: kelly ej. Sci Rep. 2021 Nov 1;11(1):21356. doi: 10.1038/s41598-021-00338-y. Sci Rep. 2021. PMID: 34725352 Free PMC article.

8

Serum Protein Exposure Activates a Core Regulatory Program Driving Human Proximal Tubule Injury.

Lidberg KA, Muthusamy S, Adil M, Mahadeo A, Yang J, Patel RS, Wang L, Bammler TK, Reichel J, Yeung CK, Himmelfarb J, Kelly EJ, Akilesh S. Lidberg KA, et al. Among authors: kelly ej. J Am Soc Nephrol. 2022 May;33(5):949-965. doi: 10.1681/ASN.2021060751. Epub 2022 Feb 23. J Am Soc Nephrol. 2022. PMID: 35197326 Free PMC article.

9

Liver and Kidney on Chips: Microphysiological Models to Understand Transporter Function.

Chang SY, Weber EJ, Ness KV, Eaton DL, Kelly EJ. Chang SY, et al. Among authors: kelly ej. Clin Pharmacol Ther. 2016 Nov;100(5):464-478. doi: 10.1002/cpt.436. Epub 2016 Aug 27. Clin Pharmacol Ther. 2016. PMID: 27448090 Free PMC article. Review.

10

Functional Coupling of Human Microphysiology Systems: Intestine, Liver, Kidney Proximal Tubule, Blood-Brain Barrier and Skeletal Muscle.

Vernetti L, Gough A, Baetz N, Blutt S, Broughman JR, Brown JA, Foulke-Abel J, Hasan N, In J, Kelly E, Kovbasnjuk O, Repper J, Senutovitch N, Stabb J, Yeung C, Zachos NC, Donowitz M, Estes M, Himmelfarb J, Truskey G, Wikswo JP, Taylor DL. Vernetti L, et al. Sci Rep. 2017 Feb 8;7:42296. doi: 10.1038/srep42296. Sci Rep. 2017. PMID: 28176881 Free PMC article.

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