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Epilepsy, hyperalgesia, impaired memory, and loss of pre- and postsynaptic GABA(B) responses in mice lacking GABA(B(1)).
Schuler V, Lüscher C, Blanchet C, Klix N, Sansig G, Klebs K, Schmutz M, Heid J, Gentry C, Urban L, Fox A, Spooren W, Jaton AL, Vigouret J, Pozza M, Kelly PH, Mosbacher J, Froestl W, Käslin E, Korn R, Bischoff S, Kaupmann K, van der Putten H, Bettler B. Schuler V, et al. Among authors: kelly ph. Neuron. 2001 Jul 19;31(1):47-58. doi: 10.1016/s0896-6273(01)00345-2. Neuron. 2001. PMID: 11498050 Free article.
Redistribution of GABAB(1) protein and atypical GABAB responses in GABAB(2)-deficient mice.
Gassmann M, Shaban H, Vigot R, Sansig G, Haller C, Barbieri S, Humeau Y, Schuler V, Müller M, Kinzel B, Klebs K, Schmutz M, Froestl W, Heid J, Kelly PH, Gentry C, Jaton AL, Van der Putten H, Mombereau C, Lecourtier L, Mosbacher J, Cryan JF, Fritschy JM, Lüthi A, Kaupmann K, Bettler B. Gassmann M, et al. Among authors: kelly ph. J Neurosci. 2004 Jul 7;24(27):6086-97. doi: 10.1523/JNEUROSCI.5635-03.2004. J Neurosci. 2004. PMID: 15240800 Free PMC article.
Behavioral characterization of the novel GABAB receptor-positive modulator GS39783 (N,N'-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine): anxiolytic-like activity without side effects associated with baclofen or benzodiazepines.
Cryan JF, Kelly PH, Chaperon F, Gentsch C, Mombereau C, Lingenhoehl K, Froestl W, Bettler B, Kaupmann K, Spooren WP. Cryan JF, et al. Among authors: kelly ph. J Pharmacol Exp Ther. 2004 Sep;310(3):952-63. doi: 10.1124/jpet.104.066753. Epub 2004 Apr 27. J Pharmacol Exp Ther. 2004. PMID: 15113848
Specific roles of GABA(B(1)) receptor isoforms in cognition.
Jacobson LH, Kelly PH, Bettler B, Kaupmann K, Cryan JF. Jacobson LH, et al. Among authors: kelly ph. Behav Brain Res. 2007 Jul 19;181(1):158-62. doi: 10.1016/j.bbr.2007.03.033. Epub 2007 Apr 5. Behav Brain Res. 2007. PMID: 17498817 Free PMC article.
mGluR7 facilitates extinction of aversive memories and controls amygdala plasticity.
Fendt M, Schmid S, Thakker DR, Jacobson LH, Yamamoto R, Mitsukawa K, Maier R, Natt F, Hüsken D, Kelly PH, McAllister KH, Hoyer D, van der Putten H, Cryan JF, Flor PJ. Fendt M, et al. Among authors: kelly ph. Mol Psychiatry. 2008 Oct;13(10):970-9. doi: 10.1038/sj.mp.4002073. Epub 2007 Aug 21. Mol Psychiatry. 2008. PMID: 17712315
Progressive age-related impairment of cognitive behavior in APP23 transgenic mice.
Kelly PH, Bondolfi L, Hunziker D, Schlecht HP, Carver K, Maguire E, Abramowski D, Wiederhold KH, Sturchler-Pierrat C, Jucker M, Bergmann R, Staufenbiel M, Sommer B. Kelly PH, et al. Neurobiol Aging. 2003 Mar-Apr;24(2):365-78. doi: 10.1016/s0197-4580(02)00098-2. Neurobiol Aging. 2003. PMID: 12498971
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