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Interaction between smoking, the shared epitope, and anti-cyclic citrullinated peptide: a mixed picture in three large North American rheumatoid arthritis cohorts.
Lee HS, Irigoyen P, Kern M, Lee A, Batliwalla F, Khalili H, Wolfe F, Lum RF, Massarotti E, Weisman M, Bombardier C, Karlson EW, Criswell LA, Vlietinck R, Gregersen PK. Lee HS, et al. Among authors: kern m. Arthritis Rheum. 2007 Jun;56(6):1745-53. doi: 10.1002/art.22703. Arthritis Rheum. 2007. PMID: 17530703 Free article.
Regulation of anti-cyclic citrullinated peptide antibodies in rheumatoid arthritis: contrasting effects of HLA-DR3 and the shared epitope alleles.
Irigoyen P, Lee AT, Wener MH, Li W, Kern M, Batliwalla F, Lum RF, Massarotti E, Weisman M, Bombardier C, Remmers EF, Kastner DL, Seldin MF, Criswell LA, Gregersen PK. Irigoyen P, et al. Among authors: kern m. Arthritis Rheum. 2005 Dec;52(12):3813-8. doi: 10.1002/art.21419. Arthritis Rheum. 2005. PMID: 16320316 Free article.
Rheumatoid arthritis risk allele PTPRC is also associated with response to anti-tumor necrosis factor alpha therapy.
Cui J, Saevarsdottir S, Thomson B, Padyukov L, van der Helm-van Mil AH, Nititham J, Hughes LB, de Vries N, Raychaudhuri S, Alfredsson L, Askling J, Wedrén S, Ding B, Guiducci C, Wolbink GJ, Crusius JB, van der Horst-Bruinsma IE, Herenius M, Weinblatt ME, Shadick NA, Worthington J, Batliwalla F, Kern M, Morgan AW, Wilson AG, Isaacs JD, Hyrich K, Seldin MF, Moreland LW, Behrens TW, Allaart CF, Criswell LA, Huizinga TW, Tak PP, Bridges SL Jr, Toes RE, Barton A, Klareskog L, Gregersen PK, Karlson EW, Plenge RM. Cui J, et al. Among authors: kern m. Arthritis Rheum. 2010 Jul;62(7):1849-61. doi: 10.1002/art.27457. Arthritis Rheum. 2010. PMID: 20309874 Free PMC article.
Modular analysis of peripheral blood gene expression in rheumatoid arthritis captures reproducible gene expression changes in tumor necrosis factor responders.
Oswald M, Curran ME, Lamberth SL, Townsend RM, Hamilton JD, Chernoff DN, Carulli J, Townsend MJ, Weinblatt ME, Kern M, Pond CM, Lee A, Gregersen PK. Oswald M, et al. Among authors: kern m. Arthritis Rheumatol. 2015 Feb;67(2):344-51. doi: 10.1002/art.38947. Arthritis Rheumatol. 2015. PMID: 25371395 Free PMC article.
Peripheral blood gene expression profiling in rheumatoid arthritis.
Batliwalla FM, Baechler EC, Xiao X, Li W, Balasubramanian S, Khalili H, Damle A, Ortmann WA, Perrone A, Kantor AB, Gulko PS, Kern M, Furie R, Behrens TW, Gregersen PK. Batliwalla FM, et al. Among authors: kern m. Genes Immun. 2005 Aug;6(5):388-97. doi: 10.1038/sj.gene.6364209. Genes Immun. 2005. PMID: 15973463
Association of a single-nucleotide polymorphism in CD40 with the rate of joint destruction in rheumatoid arthritis.
van der Linden MP, Feitsma AL, le Cessie S, Kern M, Olsson LM, Raychaudhuri S, Begovich AB, Chang M, Catanese JJ, Kurreeman FA, van Nies J, van der Heijde DM, Gregersen PK, Huizinga TW, Toes RE, van der Helm-Van Mil AH. van der Linden MP, et al. Among authors: kern m. Arthritis Rheum. 2009 Aug;60(8):2242-7. doi: 10.1002/art.24721. Arthritis Rheum. 2009. PMID: 19644859 Free PMC article.
A genomewide screen in multiplex rheumatoid arthritis families suggests genetic overlap with other autoimmune diseases.
Jawaheer D, Seldin MF, Amos CI, Chen WV, Shigeta R, Monteiro J, Kern M, Criswell LA, Albani S, Nelson JL, Clegg DO, Pope R, Schroeder HW Jr, Bridges SL Jr, Pisetsky DS, Ward R, Kastner DL, Wilder RL, Pincus T, Callahan LF, Flemming D, Wener MH, Gregersen PK. Jawaheer D, et al. Among authors: kern m. Am J Hum Genet. 2001 Apr;68(4):927-36. doi: 10.1086/319518. Epub 2001 Mar 9. Am J Hum Genet. 2001. PMID: 11254450 Free PMC article.
1,818 results