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Identification of MLH2/hPMS1 dominant mutations that prevent DNA mismatch repair function.
Commun Biol. 2020 Dec 10;3(1):751. doi: 10.1038/s42003-020-01481-4.
Commun Biol. 2020.
PMID: 33303966
Free PMC article.
Mlh2 is an accessory factor for DNA mismatch repair in Saccharomyces cerevisiae.
Campbell CS, Hombauer H, Srivatsan A, Bowen N, Gries K, Desai A, Putnam CD, Kolodner RD.
Campbell CS, et al. Among authors: gries k.
PLoS Genet. 2014 May 8;10(5):e1004327. doi: 10.1371/journal.pgen.1004327. eCollection 2014 May.
PLoS Genet. 2014.
PMID: 24811092
Free PMC article.
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A genetic screen pinpoints ribonucleotide reductase residues that sustain dNTP homeostasis and specifies a highly mutagenic type of dNTP imbalance.
Schmidt TT, Sharma S, Reyes GX, Gries K, Gross M, Zhao B, Yuan JH, Wade R, Chabes A, Hombauer H.
Schmidt TT, et al. Among authors: gries k.
Nucleic Acids Res. 2019 Jan 10;47(1):237-252. doi: 10.1093/nar/gky1154.
Nucleic Acids Res. 2019.
PMID: 30462295
Free PMC article.
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Alterations in cellular metabolism triggered by URA7 or GLN3 inactivation cause imbalanced dNTP pools and increased mutagenesis.
Schmidt TT, Reyes G, Gries K, Ceylan CÜ, Sharma S, Meurer M, Knop M, Chabes A, Hombauer H.
Schmidt TT, et al. Among authors: gries k.
Proc Natl Acad Sci U S A. 2017 May 30;114(22):E4442-E4451. doi: 10.1073/pnas.1618714114. Epub 2017 Apr 17.
Proc Natl Acad Sci U S A. 2017.
PMID: 28416670
Free PMC article.
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