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Gaucher's disease and cancer: a sphingolipid perspective.
Barth BM, Shanmugavelandy SS, Tacelosky DM, Kester M, Morad SA, Cabot MC. Barth BM, et al. Among authors: kester m. Crit Rev Oncog. 2013;18(3):221-34. doi: 10.1615/critrevoncog.2013005814. Crit Rev Oncog. 2013. PMID: 23510065 Free PMC article. Review.
Ceramide-based therapeutics for the treatment of cancer.
Barth BM, Cabot MC, Kester M. Barth BM, et al. Among authors: kester m. Anticancer Agents Med Chem. 2011 Nov;11(9):911-9. doi: 10.2174/187152011797655177. Anticancer Agents Med Chem. 2011. PMID: 21707481 Review.
Modification of sphingolipid metabolism by tamoxifen and N-desmethyltamoxifen in acute myelogenous leukemia--Impact on enzyme activity and response to cytotoxics.
Morad SA, Tan SF, Feith DJ, Kester M, Claxton DF, Loughran TP Jr, Barth BM, Fox TE, Cabot MC. Morad SA, et al. Among authors: kester m. Biochim Biophys Acta. 2015 Jul;1851(7):919-28. doi: 10.1016/j.bbalip.2015.03.001. Epub 2015 Mar 10. Biochim Biophys Acta. 2015. PMID: 25769964 Free PMC article.
Chemotherapy selection pressure alters sphingolipid composition and mitochondrial bioenergetics in resistant HL-60 cells.
Kao LP, Morad SAF, Davis TS, MacDougall MR, Kassai M, Abdelmageed N, Fox TE, Kester M, Loughran TP Jr, Abad JL, Fabrias G, Tan SF, Feith DJ, Claxton DF, Spiegel S, Fisher-Wellman KH, Cabot MC. Kao LP, et al. Among authors: kester m. J Lipid Res. 2019 Sep;60(9):1590-1602. doi: 10.1194/jlr.RA119000251. Epub 2019 Jul 30. J Lipid Res. 2019. PMID: 31363040 Free PMC article.
Combinatorial therapies improve the therapeutic efficacy of nanoliposomal ceramide for pancreatic cancer.
Jiang Y, DiVittore NA, Kaiser JM, Shanmugavelandy SS, Fritz JL, Heakal Y, Tagaram HR, Cheng H, Cabot MC, Staveley-O'Carroll KF, Tran MA, Fox TE, Barth BM, Kester M. Jiang Y, et al. Among authors: kester m. Cancer Biol Ther. 2011 Oct 1;12(7):574-85. doi: 10.4161/cbt.12.7.15971. Epub 2011 Oct 1. Cancer Biol Ther. 2011. PMID: 21795855 Free PMC article.
The therapeutic potential of nanoscale sphingolipid technologies.
Hankins JL, Doshi UA, Haakenson JK, Young MM, Barth BM, Kester M. Hankins JL, et al. Among authors: kester m. Handb Exp Pharmacol. 2013;(215):197-210. doi: 10.1007/978-3-7091-1368-4_11. Handb Exp Pharmacol. 2013. PMID: 23579457 Review.
Acid ceramidase is upregulated in AML and represents a novel therapeutic target.
Tan SF, Liu X, Fox TE, Barth BM, Sharma A, Turner SD, Awwad A, Dewey A, Doi K, Spitzer B, Shah MV, Morad SA, Desai D, Amin S, Zhu J, Liao J, Yun J, Kester M, Claxton DF, Wang HG, Cabot MC, Schuchman EH, Levine RL, Feith DJ, Loughran TP Jr. Tan SF, et al. Among authors: kester m. Oncotarget. 2016 Dec 13;7(50):83208-83222. doi: 10.18632/oncotarget.13079. Oncotarget. 2016. PMID: 27825124 Free PMC article.
467 results