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Page 1
ER-directed TREX1 limits cGAS activation at micronuclei.
Mol Cell. 2021 Feb 18;81(4):724-738.e9. doi: 10.1016/j.molcel.2020.12.037. Epub 2021 Jan 20.
Mol Cell. 2021.
PMID: 33476576
Free PMC article.
Mechanisms of APOBEC3 mutagenesis in human cancer cells.
Petljak M, Dananberg A, Chu K, Bergstrom EN, Striepen J, von Morgen P, Chen Y, Shah H, Sale JE, Alexandrov LB, Stratton MR, Maciejowski J.
Petljak M, et al. Among authors: chu k.
Nature. 2022 Jul;607(7920):799-807. doi: 10.1038/s41586-022-04972-y. Epub 2022 Jul 20.
Nature. 2022.
PMID: 35859169
Free PMC article.
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Base editing sensor libraries for high-throughput engineering and functional analysis of cancer-associated single nucleotide variants.
Sánchez-Rivera FJ, Diaz BJ, Kastenhuber ER, Schmidt H, Katti A, Kennedy M, Tem V, Ho YJ, Leibold J, Paffenholz SV, Barriga FM, Chu K, Goswami S, Wuest AN, Simon JM, Tsanov KM, Chakravarty D, Zhang H, Leslie CS, Lowe SW, Dow LE.
Sánchez-Rivera FJ, et al. Among authors: chu k.
Nat Biotechnol. 2022 Jun;40(6):862-873. doi: 10.1038/s41587-021-01172-3. Epub 2022 Feb 14.
Nat Biotechnol. 2022.
PMID: 35165384
Free PMC article.
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Adding New Dimensions to 3D Cancer Models.
Chu K, Dow LE.
Chu K, et al.
Cancer Res. 2024 Mar 15;84(6):798-799. doi: 10.1158/0008-5472.CAN-24-0490.
Cancer Res. 2024.
PMID: 38335538
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APOBEC3-dependent kataegis and TREX1-driven chromothripsis during telomere crisis.
Maciejowski J, Chatzipli A, Dananberg A, Chu K, Toufektchan E, Klimczak LJ, Gordenin DA, Campbell PJ, de Lange T.
Maciejowski J, et al. Among authors: chu k.
Nat Genet. 2020 Sep;52(9):884-890. doi: 10.1038/s41588-020-0667-5. Epub 2020 Jul 27.
Nat Genet. 2020.
PMID: 32719516
Free PMC article.
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Magnesium accumulation upon cyclin M4 silencing activates microsomal triglyceride transfer protein improving NASH.
Simón J, Goikoetxea-Usandizaga N, Serrano-Maciá M, Fernández-Ramos D, Sáenz de Urturi D, Gruskos JJ, Fernández-Tussy P, Lachiondo-Ortega S, González-Recio I, Rodríguez-Agudo R, Gutiérrez-de-Juan V, Rodríguez-Iruretagoyena B, Varela-Rey M, Gimenez-Mascarell P, Mercado-Gomez M, Gómez-Santos B, Fernandez-Rodriguez C, Lopitz-Otsoa F, Bizkarguenaga M, Dames S, Schaeper U, Martin F, Sabio G, Iruzubieta P, Crespo J, Aspichueta P, Chu KH, Buccella D, Martín C, Delgado TC, Martínez-Cruz LA, Martínez-Chantar ML.
Simón J, et al. Among authors: chu kh.
J Hepatol. 2021 Jul;75(1):34-45. doi: 10.1016/j.jhep.2021.01.043. Epub 2021 Feb 9.
J Hepatol. 2021.
PMID: 33571553
Free PMC article.
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