Khelashvili G - Search Results

1

GPCR-OKB: the G Protein Coupled Receptor Oligomer Knowledge Base.

Khelashvili G, Dorff K, Shan J, Camacho-Artacho M, Skrabanek L, Vroling B, Bouvier M, Devi LA, George SR, Javitch JA, Lohse MJ, Milligan G, Neubig RR, Palczewski K, Parmentier M, Pin JP, Vriend G, Campagne F, Filizola M. Khelashvili G, et al. Bioinformatics. 2010 Jul 15;26(14):1804-5. doi: 10.1093/bioinformatics/btq264. Epub 2010 May 25. Bioinformatics. 2010. PMID: 20501551 Free PMC article.

2

Quantitative modeling of membrane deformations by multihelical membrane proteins: application to G-protein coupled receptors.

Mondal S, Khelashvili G, Shan J, Andersen OS, Weinstein H. Mondal S, et al. Among authors: khelashvili g. Biophys J. 2011 Nov 2;101(9):2092-101. doi: 10.1016/j.bpj.2011.09.037. Epub 2011 Nov 1. Biophys J. 2011. PMID: 22067146 Free PMC article.

3

Ligand-dependent conformations and dynamics of the serotonin 5-HT(2A) receptor determine its activation and membrane-driven oligomerization properties.

Shan J, Khelashvili G, Mondal S, Mehler EL, Weinstein H. Shan J, et al. Among authors: khelashvili g. PLoS Comput Biol. 2012;8(4):e1002473. doi: 10.1371/journal.pcbi.1002473. Epub 2012 Apr 19. PLoS Comput Biol. 2012. PMID: 22532793 Free PMC article.

4

The membrane protein LeuT in micellar systems: aggregation dynamics and detergent binding to the S2 site.

Khelashvili G, LeVine MV, Shi L, Quick M, Javitch JA, Weinstein H. Khelashvili G, et al. J Am Chem Soc. 2013 Sep 25;135(38):14266-75. doi: 10.1021/ja405984v. Epub 2013 Sep 16. J Am Chem Soc. 2013. PMID: 23980525 Free PMC article.

5

Membrane driven spatial organization of GPCRs.

Mondal S, Johnston JM, Wang H, Khelashvili G, Filizola M, Weinstein H. Mondal S, et al. Among authors: khelashvili g. Sci Rep. 2013 Oct 9;3:2909. doi: 10.1038/srep02909. Sci Rep. 2013. PMID: 24105260 Free PMC article.

6

How the dynamic properties and functional mechanisms of GPCRs are modulated by their coupling to the membrane environment.

Mondal S, Khelashvili G, Johner N, Weinstein H. Mondal S, et al. Among authors: khelashvili g. Adv Exp Med Biol. 2014;796:55-74. doi: 10.1007/978-94-007-7423-0_4. Adv Exp Med Biol. 2014. PMID: 24158801 Review.

7

PIP2 regulates psychostimulant behaviors through its interaction with a membrane protein.

Hamilton PJ, Belovich AN, Khelashvili G, Saunders C, Erreger K, Javitch JA, Sitte HH, Weinstein H, Matthies HJG, Galli A. Hamilton PJ, et al. Among authors: khelashvili g. Nat Chem Biol. 2014 Jul;10(7):582-589. doi: 10.1038/nchembio.1545. Epub 2014 Jun 1. Nat Chem Biol. 2014. PMID: 24880859 Free PMC article.

8

A functional selectivity mechanism at the serotonin-2A GPCR involves ligand-dependent conformations of intracellular loop 2.

Perez-Aguilar JM, Shan J, LeVine MV, Khelashvili G, Weinstein H. Perez-Aguilar JM, et al. Among authors: khelashvili g. J Am Chem Soc. 2014 Nov 12;136(45):16044-54. doi: 10.1021/ja508394x. Epub 2014 Oct 31. J Am Chem Soc. 2014. PMID: 25314362 Free PMC article.

9

Mechanism of the Association between Na+ Binding and Conformations at the Intracellular Gate in Neurotransmitter:Sodium Symporters.

Stolzenberg S, Quick M, Zhao C, Gotfryd K, Khelashvili G, Gether U, Loland CJ, Javitch JA, Noskov S, Weinstein H, Shi L. Stolzenberg S, et al. Among authors: khelashvili g. J Biol Chem. 2015 May 29;290(22):13992-4003. doi: 10.1074/jbc.M114.625343. Epub 2015 Apr 13. J Biol Chem. 2015. PMID: 25869126 Free PMC article.

10

Role of Annular Lipids in the Functional Properties of Leucine Transporter LeuT Proteomicelles.

LeVine MV, Khelashvili G, Shi L, Quick M, Javitch JA, Weinstein H. LeVine MV, et al. Among authors: khelashvili g. Biochemistry. 2016 Feb 16;55(6):850-9. doi: 10.1021/acs.biochem.5b01268. Epub 2016 Feb 5. Biochemistry. 2016. PMID: 26811944 Free PMC article.

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