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2019 1
2020 2
2021 1
2022 1
2024 0

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Page 1
Inherited myeloproliferative neoplasm risk affects haematopoietic stem cells.
Bao EL, Nandakumar SK, Liao X, Bick AG, Karjalainen J, Tabaka M, Gan OI, Havulinna AS, Kiiskinen TTJ, Lareau CA, de Lapuente Portilla AL, Li B, Emdin C, Codd V, Nelson CP, Walker CJ, Churchhouse C, de la Chapelle A, Klein DE, Nilsson B, Wilson PWF, Cho K, Pyarajan S, Gaziano JM, Samani NJ; FinnGen; 23andMe Research Team; Regev A, Palotie A, Neale BM, Dick JE, Natarajan P, O'Donnell CJ, Daly MJ, Milyavsky M, Kathiresan S, Sankaran VG. Bao EL, et al. Among authors: kiiskinen ttj. Nature. 2020 Oct;586(7831):769-775. doi: 10.1038/s41586-020-2786-7. Epub 2020 Oct 14. Nature. 2020. PMID: 33057200 Free PMC article.
Mendelian randomization of genetically independent aging phenotypes identifies LPA and VCAM1 as biological targets for human aging.
Timmers PRHJ, Tiys ES, Sakaue S, Akiyama M, Kiiskinen TTJ, Zhou W, Hwang SJ, Yao C; Biobank Japan Project; FinnGen; Deelen J, Levy D, Ganna A, Kamatani Y, Okada Y, Joshi PK, Wilson JF, Tsepilov YA. Timmers PRHJ, et al. Among authors: kiiskinen ttj. Nat Aging. 2022 Jan;2(1):19-30. doi: 10.1038/s43587-021-00159-8. Epub 2022 Jan 20. Nat Aging. 2022. PMID: 37118362
Genetic architecture of human plasma lipidome and its link to cardiovascular disease.
Tabassum R, Rämö JT, Ripatti P, Koskela JT, Kurki M, Karjalainen J, Palta P, Hassan S, Nunez-Fontarnau J, Kiiskinen TTJ, Söderlund S, Matikainen N, Gerl MJ, Surma MA, Klose C, Stitziel NO, Laivuori H, Havulinna AS, Service SK, Salomaa V, Pirinen M; FinnGen Project; Jauhiainen M, Daly MJ, Freimer NB, Palotie A, Taskinen MR, Simons K, Ripatti S. Tabassum R, et al. Among authors: kiiskinen ttj. Nat Commun. 2019 Sep 24;10(1):4329. doi: 10.1038/s41467-019-11954-8. Nat Commun. 2019. PMID: 31551469 Free PMC article.
Polygenic burden has broader impact on health, cognition, and socioeconomic outcomes than most rare and high-risk copy number variants.
Saarentaus EC, Havulinna AS, Mars N, Ahola-Olli A, Kiiskinen TTJ, Partanen J, Ruotsalainen S, Kurki M, Urpa LM, Chen L, Perola M, Salomaa V, Veijola J, Männikkö M, Hall IM, Pietiläinen O, Kaprio J, Ripatti S, Daly M, Palotie A. Saarentaus EC, et al. Among authors: kiiskinen ttj. Mol Psychiatry. 2021 Sep;26(9):4884-4895. doi: 10.1038/s41380-021-01026-z. Epub 2021 Feb 1. Mol Psychiatry. 2021. PMID: 33526825 Free PMC article.
Polygenic and clinical risk scores and their impact on age at onset and prediction of cardiometabolic diseases and common cancers.
Mars N, Koskela JT, Ripatti P, Kiiskinen TTJ, Havulinna AS, Lindbohm JV, Ahola-Olli A, Kurki M, Karjalainen J, Palta P; FinnGen; Neale BM, Daly M, Salomaa V, Palotie A, Widén E, Ripatti S. Mars N, et al. Among authors: kiiskinen ttj. Nat Med. 2020 Apr;26(4):549-557. doi: 10.1038/s41591-020-0800-0. Epub 2020 Apr 7. Nat Med. 2020. PMID: 32273609