Kim J - Search Results

1

A tyrosine kinase inhibitor-induced interferon response positively associates with clinical response in EGFR-mutant lung cancer.

Gurule NJ, McCoach CE, Hinz TK, Merrick DT, Van Bokhoven A, Kim J, Patil T, Calhoun J, Nemenoff RA, Tan AC, Doebele RC, Heasley LE. Gurule NJ, et al. Among authors: kim j. NPJ Precis Oncol. 2021 May 17;5(1):41. doi: 10.1038/s41698-021-00181-4. NPJ Precis Oncol. 2021. PMID: 34001994 Free PMC article.

2

A receptor tyrosine kinase network composed of fibroblast growth factor receptors, epidermal growth factor receptor, v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, and hepatocyte growth factor receptor drives growth and survival of head and neck squamous carcinoma cell lines.

Singleton KR, Kim J, Hinz TK, Marek LA, Casás-Selves M, Hatheway C, Tan AC, DeGregori J, Heasley LE. Singleton KR, et al. Among authors: kim j. Mol Pharmacol. 2013 Apr;83(4):882-93. doi: 10.1124/mol.112.084111. Epub 2013 Jan 31. Mol Pharmacol. 2013. PMID: 23371912 Free PMC article.

3

Bioinformatics-driven discovery of rational combination for overcoming EGFR-mutant lung cancer resistance to EGFR therapy.

Kim J, Vasu VT, Mishra R, Singleton KR, Yoo M, Leach SM, Farias-Hesson E, Mason RJ, Kang J, Ramamoorthy P, Kern JA, Heasley LE, Finigan JH, Tan AC. Kim J, et al. Bioinformatics. 2014 Sep 1;30(17):2393-8. doi: 10.1093/bioinformatics/btu323. Epub 2014 May 7. Bioinformatics. 2014. PMID: 24812339 Free PMC article.

4

Identifying kinase dependency in cancer cells by integrating high-throughput drug screening and kinase inhibition data.

Ryall KA, Shin J, Yoo M, Hinz TK, Kim J, Kang J, Heasley LE, Tan AC. Ryall KA, et al. Among authors: kim j. Bioinformatics. 2015 Dec 1;31(23):3799-806. doi: 10.1093/bioinformatics/btv427. Epub 2015 Jul 23. Bioinformatics. 2015. PMID: 26206305 Free PMC article.

5

Kinome RNAi Screens Reveal Synergistic Targeting of MTOR and FGFR1 Pathways for Treatment of Lung Cancer and HNSCC.

Singleton KR, Hinz TK, Kleczko EK, Marek LA, Kwak J, Harp T, Kim J, Tan AC, Heasley LE. Singleton KR, et al. Among authors: kim j. Cancer Res. 2015 Oct 15;75(20):4398-406. doi: 10.1158/0008-5472.CAN-15-0509. Epub 2015 Sep 10. Cancer Res. 2015. PMID: 26359452 Free PMC article.

6

ALK is a critical regulator of the MYC-signaling axis in ALK positive lung cancer.

Pilling AB, Kim J, Estrada-Bernal A, Zhou Q, Le AT, Singleton KR, Heasley LE, Tan AC, DeGregori J, Doebele RC. Pilling AB, et al. Among authors: kim j. Oncotarget. 2018 Jan 16;9(10):8823-8835. doi: 10.18632/oncotarget.24260. eCollection 2018 Feb 6. Oncotarget. 2018. PMID: 29507657 Free PMC article.

7

Functional RNAi Screens Define Distinct Protein Kinase Vulnerabilities in EGFR-Dependent HNSCC Cell Lines.

Hinz TK, Kleczko EK, Singleton KR, Calhoun J, Marek LA, Kim J, Tan AC, Heasley LE. Hinz TK, et al. Among authors: kim j. Mol Pharmacol. 2019 Dec;96(6):862-870. doi: 10.1124/mol.119.117804. Epub 2019 Sep 25. Mol Pharmacol. 2019. PMID: 31554698 Free PMC article.

8

Role of epidermal growth factor receptor inhibitor-induced interferon pathway signaling in the head and neck squamous cell carcinoma therapeutic response.

Korpela SP, Hinz TK, Oweida A, Kim J, Calhoun J, Ferris R, Nemenoff RA, Karam SD, Clambey ET, Heasley LE. Korpela SP, et al. Among authors: kim j. J Transl Med. 2021 Jan 23;19(1):43. doi: 10.1186/s12967-021-02706-8. J Transl Med. 2021. PMID: 33485341 Free PMC article.

9

BiNGS!SL-seq: a bioinformatics pipeline for the analysis and interpretation of deep sequencing genome-wide synthetic lethal screen.

Kim J, Tan AC. Kim J, et al. Methods Mol Biol. 2012;802:389-98. doi: 10.1007/978-1-61779-400-1_26. Methods Mol Biol. 2012. PMID: 22130895

10

Efficacy and Molecular Mechanisms of Differentiated Response to the Aurora and Angiogenic Kinase Inhibitor ENMD-2076 in Preclinical Models of p53-Mutated Triple-Negative Breast Cancer.

Ionkina AA, Tentler JJ, Kim J, Capasso A, Pitts TM, Ryall KA, Howison RR, Kabos P, Sartorius CA, Tan AC, Eckhardt SG, Diamond JR. Ionkina AA, et al. Among authors: kim j. Front Oncol. 2017 May 15;7:94. doi: 10.3389/fonc.2017.00094. eCollection 2017. Front Oncol. 2017. PMID: 28555173 Free PMC article.

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