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Autophagy critically controls skin inflammation and apoptosis-induced stem cell activation.
Van Hove L, Toniolo A, Ghiasloo M, Lecomte K, Boone F, Ciers M, Raaijmakers K, Vandamme N, Roels J, Maschalidi S, Ravichandran KS, Kasper M, van Loo G, Hoste E. Van Hove L, et al. Among authors: lecomte k. Autophagy. 2023 Nov;19(11):2958-2971. doi: 10.1080/15548627.2023.2247742. Epub 2023 Sep 1. Autophagy. 2023. PMID: 37615626 Free PMC article.
Targeting SLC7A11 improves efferocytosis by dendritic cells and wound healing in diabetes.
Maschalidi S, Mehrotra P, Keçeli BN, De Cleene HKL, Lecomte K, Van der Cruyssen R, Janssen P, Pinney J, van Loo G, Elewaut D, Massie A, Hoste E, Ravichandran KS. Maschalidi S, et al. Among authors: lecomte k. Nature. 2022 Jun;606(7915):776-784. doi: 10.1038/s41586-022-04754-6. Epub 2022 May 25. Nature. 2022. PMID: 35614212
OTULIN maintains skin homeostasis by controlling keratinocyte death and stem cell identity.
Hoste E, Lecomte K, Annusver K, Vandamme N, Roels J, Maschalidi S, Verboom L, Vikkula HK, Sze M, Van Hove L, Verstaen K, Martens A, Hochepied T, Saeys Y, Ravichandran K, Kasper M, van Loo G. Hoste E, et al. Among authors: lecomte k. Nat Commun. 2021 Oct 8;12(1):5913. doi: 10.1038/s41467-021-25944-2. Nat Commun. 2021. PMID: 34625556 Free PMC article.
Fibrotic enzymes modulate wound-induced skin tumorigenesis.
Van Hove L, Lecomte K, Roels J, Vandamme N, Vikkula HK, Hoorens I, Ongenae K, Hochepied T, Donati G, Saeys Y, Quist SR, Watt FM, van Loo G, Hoste E. Van Hove L, et al. Among authors: lecomte k. EMBO Rep. 2021 May 5;22(5):e51573. doi: 10.15252/embr.202051573. Epub 2021 Mar 29. EMBO Rep. 2021. PMID: 33780134 Free PMC article.