King RW - Search Results

1

Chromosome nondisjunction yields tetraploid rather than aneuploid cells in human cell lines.

Shi Q, King RW. Shi Q, et al. Among authors: king rw. Nature. 2005 Oct 13;437(7061):1038-42. doi: 10.1038/nature03958. Nature. 2005. PMID: 16222248

2

When 2+2=5: the origins and fates of aneuploid and tetraploid cells.

King RW. King RW. Biochim Biophys Acta. 2008 Sep;1786(1):4-14. doi: 10.1016/j.bbcan.2008.07.007. Epub 2008 Aug 7. Biochim Biophys Acta. 2008. PMID: 18703117 Free PMC article. Review.

3

Enhancement of proteasome activity by a small-molecule inhibitor of USP14.

Lee BH, Lee MJ, Park S, Oh DC, Elsasser S, Chen PC, Gartner C, Dimova N, Hanna J, Gygi SP, Wilson SM, King RW, Finley D. Lee BH, et al. Among authors: king rw. Nature. 2010 Sep 9;467(7312):179-84. doi: 10.1038/nature09299. Nature. 2010. PMID: 20829789 Free PMC article.

4

A non-genetic route to aneuploidy in human cancers.

Krajcovic M, Johnson NB, Sun Q, Normand G, Hoover N, Yao E, Richardson AL, King RW, Cibas ES, Schnitt SJ, Brugge JS, Overholtzer M. Krajcovic M, et al. Among authors: king rw. Nat Cell Biol. 2011 Mar;13(3):324-30. doi: 10.1038/ncb2174. Epub 2011 Feb 20. Nat Cell Biol. 2011. PMID: 21336303 Free PMC article.

5

A bioinformatics method identifies prominent off-targeted transcripts in RNAi screens.

Sigoillot FD, Lyman S, Huckins JF, Adamson B, Chung E, Quattrochi B, King RW. Sigoillot FD, et al. Among authors: king rw. Nat Methods. 2012 Feb 19;9(4):363-6. doi: 10.1038/nmeth.1898. Nat Methods. 2012. PMID: 22343343 Free PMC article.

6

Synergistic blockade of mitotic exit by two chemical inhibitors of the APC/C.

Sackton KL, Dimova N, Zeng X, Tian W, Zhang M, Sackton TB, Meaders J, Pfaff KL, Sigoillot F, Yu H, Luo X, King RW. Sackton KL, et al. Among authors: king rw. Nature. 2014 Oct 30;514(7524):646-9. doi: 10.1038/nature13660. Epub 2014 Aug 24. Nature. 2014. PMID: 25156254 Free PMC article.

7

Defective sister chromatid cohesion is synthetically lethal with impaired APC/C function.

de Lange J, Faramarz A, Oostra AB, de Menezes RX, van der Meulen IH, Rooimans MA, Rockx DA, Brakenhoff RH, van Beusechem VW, King RW, de Winter JP, Wolthuis RMF. de Lange J, et al. Among authors: king rw. Nat Commun. 2015 Oct 1;6:8399. doi: 10.1038/ncomms9399. Nat Commun. 2015. PMID: 26423134 Free PMC article.

8

USP14 deubiquitinates proteasome-bound substrates that are ubiquitinated at multiple sites.

Lee BH, Lu Y, Prado MA, Shi Y, Tian G, Sun S, Elsasser S, Gygi SP, King RW, Finley D. Lee BH, et al. Among authors: king rw. Nature. 2016 Apr 21;532(7599):398-401. doi: 10.1038/nature17433. Epub 2016 Apr 13. Nature. 2016. PMID: 27074503 Free PMC article.

9

How proteolysis drives the cell cycle.

King RW, Deshaies RJ, Peters JM, Kirschner MW. King RW, et al. Science. 1996 Dec 6;274(5293):1652-9. doi: 10.1126/science.274.5293.1652. Science. 1996. PMID: 8939846 Review.

10

Dissecting cellular processes using small molecules: identification of colchicine-like, taxol-like and other small molecules that perturb mitosis.

Haggarty SJ, Mayer TU, Miyamoto DT, Fathi R, King RW, Mitchison TJ, Schreiber SL. Haggarty SJ, et al. Among authors: king rw. Chem Biol. 2000 Apr;7(4):275-86. doi: 10.1016/s1074-5521(00)00101-0. Chem Biol. 2000. PMID: 10780927

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