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Blocking IL-6 trans-signaling prevents high-fat diet-induced adipose tissue macrophage recruitment but does not improve insulin resistance.
Kraakman MJ, Kammoun HL, Allen TL, Deswaerte V, Henstridge DC, Estevez E, Matthews VB, Neill B, White DA, Murphy AJ, Peijs L, Yang C, Risis S, Bruce CR, Du XJ, Bobik A, Lee-Young RS, Kingwell BA, Vasanthakumar A, Shi W, Kallies A, Lancaster GI, Rose-John S, Febbraio MA. Kraakman MJ, et al. Among authors: kingwell ba. Cell Metab. 2015 Mar 3;21(3):403-16. doi: 10.1016/j.cmet.2015.02.006. Cell Metab. 2015. PMID: 25738456 Free article.
Fetuin B Is a Secreted Hepatocyte Factor Linking Steatosis to Impaired Glucose Metabolism.
Meex RC, Hoy AJ, Morris A, Brown RD, Lo JC, Burke M, Goode RJ, Kingwell BA, Kraakman MJ, Febbraio MA, Greve JW, Rensen SS, Molloy MP, Lancaster GI, Bruce CR, Watt MJ. Meex RC, et al. Among authors: kingwell ba. Cell Metab. 2015 Dec 1;22(6):1078-89. doi: 10.1016/j.cmet.2015.09.023. Epub 2015 Oct 22. Cell Metab. 2015. PMID: 26603189 Free article.
Genetic manipulation of cardiac Hsp72 levels does not alter substrate metabolism but reveals insights into high-fat feeding-induced cardiac insulin resistance.
Henstridge DC, Estevez E, Allen TL, Heywood SE, Gardner T, Yang C, Mellett NA, Kingwell BA, Meikle PJ, Febbraio MA. Henstridge DC, et al. Among authors: kingwell ba. Cell Stress Chaperones. 2015 May;20(3):461-72. doi: 10.1007/s12192-015-0571-6. Epub 2015 Jan 25. Cell Stress Chaperones. 2015. PMID: 25618331 Free PMC article.
HSP72 protects against obesity-induced insulin resistance.
Chung J, Nguyen AK, Henstridge DC, Holmes AG, Chan MH, Mesa JL, Lancaster GI, Southgate RJ, Bruce CR, Duffy SJ, Horvath I, Mestril R, Watt MJ, Hooper PL, Kingwell BA, Vigh L, Hevener A, Febbraio MA. Chung J, et al. Among authors: kingwell ba. Proc Natl Acad Sci U S A. 2008 Feb 5;105(5):1739-44. doi: 10.1073/pnas.0705799105. Epub 2008 Jan 25. Proc Natl Acad Sci U S A. 2008. PMID: 18223156 Free PMC article.
Interleukin-6 attenuates insulin-mediated increases in endothelial cell signaling but augments skeletal muscle insulin action via differential effects on tumor necrosis factor-alpha expression.
Yuen DY, Dwyer RM, Matthews VB, Zhang L, Drew BG, Neill B, Kingwell BA, Clark MG, Rattigan S, Febbraio MA. Yuen DY, et al. Among authors: kingwell ba. Diabetes. 2009 May;58(5):1086-95. doi: 10.2337/db08-0775. Epub 2009 Feb 2. Diabetes. 2009. PMID: 19188427 Free PMC article.
Deletion of macrophage migration inhibitory factor protects the heart from severe ischemia-reperfusion injury: a predominant role of anti-inflammation.
Gao XM, Liu Y, White D, Su Y, Drew BG, Bruce CR, Kiriazis H, Xu Q, Jennings N, Bobik A, Febbraio MA, Kingwell BA, Bucala R, Fingerle-Rowson G, Dart AM, Morand EF, Du XJ. Gao XM, et al. Among authors: kingwell ba. J Mol Cell Cardiol. 2011 Jun;50(6):991-9. doi: 10.1016/j.yjmcc.2010.12.022. Epub 2011 Jan 6. J Mol Cell Cardiol. 2011. PMID: 21215754
Glucose-6-phosphate dehydrogenase contributes to the regulation of glucose uptake in skeletal muscle.
Lee-Young RS, Hoffman NJ, Murphy KT, Henstridge DC, Samocha-Bonet D, Siebel AL, Iliades P, Zivanovic B, Hong YH, Colgan TD, Kraakman MJ, Bruce CR, Gregorevic P, McConell GK, Lynch GS, Drummond GR, Kingwell BA, Greenfield JR, Febbraio MA. Lee-Young RS, et al. Among authors: kingwell ba. Mol Metab. 2016 Sep 9;5(11):1083-1091. doi: 10.1016/j.molmet.2016.09.002. eCollection 2016 Nov. Mol Metab. 2016. PMID: 27818934 Free PMC article.
254 results