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A serum-stable RNA aptamer specific for SARS-CoV-2 neutralizes viral entry.
Valero J, Civit L, Dupont DM, Selnihhin D, Reinert LS, Idorn M, Israels BA, Bednarz AM, Bus C, Asbach B, Peterhoff D, Pedersen FS, Birkedal V, Wagner R, Paludan SR, Kjems J. Valero J, et al. Among authors: kjems j. Proc Natl Acad Sci U S A. 2021 Dec 14;118(50):e2112942118. doi: 10.1073/pnas.2112942118. Proc Natl Acad Sci U S A. 2021. PMID: 34876524 Free PMC article.
Molecular strategies to inhibit HIV-1 replication.
Nielsen MH, Pedersen FS, Kjems J. Nielsen MH, et al. Among authors: kjems j. Retrovirology. 2005 Feb 16;2:10. doi: 10.1186/1742-4690-2-10. Retrovirology. 2005. PMID: 15715913 Free PMC article. Review.
Seemingly neutral polymorphic variants may confer immunity to splicing-inactivating mutations: a synonymous SNP in exon 5 of MCAD protects from deleterious mutations in a flanking exonic splicing enhancer.
Nielsen KB, Sørensen S, Cartegni L, Corydon TJ, Doktor TK, Schroeder LD, Reinert LS, Elpeleg O, Krainer AR, Gregersen N, Kjems J, Andresen BS. Nielsen KB, et al. Among authors: kjems j. Am J Hum Genet. 2007 Mar;80(3):416-32. doi: 10.1086/511992. Epub 2007 Jan 18. Am J Hum Genet. 2007. PMID: 17273963 Free PMC article.
Delivery of siRNA from lyophilized polymeric surfaces.
Andersen MØ, Howard KA, Paludan SR, Besenbacher F, Kjems J. Andersen MØ, et al. Among authors: kjems j. Biomaterials. 2008 Feb;29(4):506-12. doi: 10.1016/j.biomaterials.2007.10.003. Epub 2007 Oct 24. Biomaterials. 2008. PMID: 17950838
A screen of chemical modifications identifies position-specific modification by UNA to most potently reduce siRNA off-target effects.
Bramsen JB, Pakula MM, Hansen TB, Bus C, Langkjær N, Odadzic D, Smicius R, Wengel SL, Chattopadhyaya J, Engels JW, Herdewijn P, Wengel J, Kjems J. Bramsen JB, et al. Among authors: kjems j. Nucleic Acids Res. 2010 Sep;38(17):5761-73. doi: 10.1093/nar/gkq341. Epub 2010 May 7. Nucleic Acids Res. 2010. PMID: 20453030 Free PMC article.
380 results