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A20 regulates lymphocyte adhesion in murine neuroinflammation by restricting endothelial ICOSL expression in the CNS.
Johann L, Soldati S, Müller K, Lampe J, Marini F, Klein M, Schramm E, Ries N, Schelmbauer C, Palagi I, Karram K, Assmann JC, Khan MA, Wenzel J, Schmidt MH, Körbelin J, Schlüter D, van Loo G, Bopp T, Engelhardt B, Schwaninger M, Waisman A. Johann L, et al. Among authors: klein m. J Clin Invest. 2023 Dec 15;133(24):e168314. doi: 10.1172/JCI168314. J Clin Invest. 2023. PMID: 37856217 Free PMC article.
Microglial A20 Protects the Brain from CD8 T-Cell-Mediated Immunopathology.
Mohebiany AN, Ramphal NS, Karram K, Di Liberto G, Novkovic T, Klein M, Marini F, Kreutzfeldt M, Härtner F, Lacher SM, Bopp T, Mittmann T, Merkler D, Waisman A. Mohebiany AN, et al. Among authors: klein m. Cell Rep. 2020 Feb 4;30(5):1585-1597.e6. doi: 10.1016/j.celrep.2019.12.097. Cell Rep. 2020. PMID: 32023471 Free article.
Interleukin-1 promotes autoimmune neuroinflammation by suppressing endothelial heme oxygenase-1 at the blood-brain barrier.
Hauptmann J, Johann L, Marini F, Kitic M, Colombo E, Mufazalov IA, Krueger M, Karram K, Moos S, Wanke F, Kurschus FC, Klein M, Cardoso S, Strauß J, Bolisetty S, Lühder F, Schwaninger M, Binder H, Bechman I, Bopp T, Agarwal A, Soares MP, Regen T, Waisman A. Hauptmann J, et al. Among authors: klein m. Acta Neuropathol. 2020 Oct;140(4):549-567. doi: 10.1007/s00401-020-02187-x. Epub 2020 Jul 11. Acta Neuropathol. 2020. PMID: 32651669 Free PMC article.
Th9 cells, new players in adaptive immunity.
Schmitt E, Klein M, Bopp T. Schmitt E, et al. Among authors: klein m. Trends Immunol. 2014 Feb;35(2):61-8. doi: 10.1016/j.it.2013.10.004. Epub 2013 Nov 8. Trends Immunol. 2014. PMID: 24215739 Review.
Genetic Cell Ablation Reveals Clusters of Local Self-Renewing Microglia in the Mammalian Central Nervous System.
Bruttger J, Karram K, Wörtge S, Regen T, Marini F, Hoppmann N, Klein M, Blank T, Yona S, Wolf Y, Mack M, Pinteaux E, Müller W, Zipp F, Binder H, Bopp T, Prinz M, Jung S, Waisman A. Bruttger J, et al. Among authors: klein m. Immunity. 2015 Jul 21;43(1):92-106. doi: 10.1016/j.immuni.2015.06.012. Epub 2015 Jul 7. Immunity. 2015. PMID: 26163371 Free article.
IL-17 controls central nervous system autoimmunity through the intestinal microbiome.
Regen T, Isaac S, Amorim A, Núñez NG, Hauptmann J, Shanmugavadivu A, Klein M, Sankowski R, Mufazalov IA, Yogev N, Huppert J, Wanke F, Witting M, Grill A, Gálvez EJC, Nikolaev A, Blanfeld M, Prinz I, Schmitt-Kopplin P, Strowig T, Reinhardt C, Prinz M, Bopp T, Becher B, Ubeda C, Waisman A. Regen T, et al. Among authors: klein m. Sci Immunol. 2021 Feb 5;6(56):eaaz6563. doi: 10.1126/sciimmunol.aaz6563. Sci Immunol. 2021. PMID: 33547052
Impaired Treg-DC interactions contribute to autoimmunity in leukocyte adhesion deficiency type 1.
Klaus T, Wilson AS, Vicari E, Hadaschik E, Klein M, Helbich SSC, Kamenjarin N, Hodapp K, Schunke J, Haist M, Butsch F, Probst HC, Enk AH, Mahnke K, Waisman A, Bednarczyk M, Bros M, Bopp T, Grabbe S. Klaus T, et al. Among authors: klein m. JCI Insight. 2022 Dec 22;7(24):e162580. doi: 10.1172/jci.insight.162580. JCI Insight. 2022. PMID: 36346673 Free PMC article.
Protein kinase CK2 governs the molecular decision between encephalitogenic TH17 cell and Treg cell development.
Ulges A, Witsch EJ, Pramanik G, Klein M, Birkner K, Bühler U, Wasser B, Luessi F, Stergiou N, Dietzen S, Brühl TJ, Bohn T, Bündgen G, Kunz H, Waisman A, Schild H, Schmitt E, Zipp F, Bopp T. Ulges A, et al. Among authors: klein m. Proc Natl Acad Sci U S A. 2016 Sep 6;113(36):10145-50. doi: 10.1073/pnas.1523869113. Epub 2016 Aug 23. Proc Natl Acad Sci U S A. 2016. PMID: 27555590 Free PMC article.
6,565 results