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Triggering the adaptive immune system with commensal gut bacteria protects against insulin resistance and dysglycemia.
Pomié C, Blasco-Baque V, Klopp P, Nicolas S, Waget A, Loubières P, Azalbert V, Puel A, Lopez F, Dray C, Valet P, Lelouvier B, Servant F, Courtney M, Amar J, Burcelin R, Garidou L. Pomié C, et al. Among authors: klopp p. Mol Metab. 2016 Mar 28;5(6):392-403. doi: 10.1016/j.molmet.2016.03.004. eCollection 2016 Jun. Mol Metab. 2016. PMID: 27257599 Free PMC article.
The Gut Microbiota Regulates Intestinal CD4 T Cells Expressing RORγt and Controls Metabolic Disease.
Garidou L, Pomié C, Klopp P, Waget A, Charpentier J, Aloulou M, Giry A, Serino M, Stenman L, Lahtinen S, Dray C, Iacovoni JS, Courtney M, Collet X, Amar J, Servant F, Lelouvier B, Valet P, Eberl G, Fazilleau N, Douin-Echinard V, Heymes C, Burcelin R. Garidou L, et al. Among authors: klopp p. Cell Metab. 2015 Jul 7;22(1):100-12. doi: 10.1016/j.cmet.2015.06.001. Cell Metab. 2015. PMID: 26154056 Free article.
Periodontitis induced by Porphyromonas gingivalis drives periodontal microbiota dysbiosis and insulin resistance via an impaired adaptive immune response.
Blasco-Baque V, Garidou L, Pomié C, Escoula Q, Loubieres P, Le Gall-David S, Lemaitre M, Nicolas S, Klopp P, Waget A, Azalbert V, Colom A, Bonnaure-Mallet M, Kemoun P, Serino M, Burcelin R. Blasco-Baque V, et al. Among authors: klopp p. Gut. 2017 May;66(5):872-885. doi: 10.1136/gutjnl-2015-309897. Epub 2016 Feb 2. Gut. 2017. PMID: 26838600 Free PMC article.
Transfer of dysbiotic gut microbiota has beneficial effects on host liver metabolism.
Nicolas S, Blasco-Baque V, Fournel A, Gilleron J, Klopp P, Waget A, Ceppo F, Marlin A, Padmanabhan R, Iacovoni JS, Tercé F, Cani PD, Tanti JF, Burcelin R, Knauf C, Cormont M, Serino M. Nicolas S, et al. Among authors: klopp p. Mol Syst Biol. 2017 Mar 16;13(3):921. doi: 10.15252/msb.20167356. Mol Syst Biol. 2017. PMID: 28302863 Free PMC article.
CX3CR1 regulates gut microbiota and metabolism. A risk factor of type 2 diabetes.
Pomié C, Servant F, Garidou L, Azalbert V, Waget A, Klopp P, Garret C, Charpentier J, Briand F, Sulpice T, Lelouvier B, Douin-Echinard V, Burcelin R. Pomié C, et al. Among authors: klopp p. Acta Diabetol. 2021 Aug;58(8):1035-1049. doi: 10.1007/s00592-021-01682-1. Epub 2021 Mar 22. Acta Diabetol. 2021. PMID: 33754166
Intestinal mucosal adherence and translocation of commensal bacteria at the early onset of type 2 diabetes: molecular mechanisms and probiotic treatment.
Amar J, Chabo C, Waget A, Klopp P, Vachoux C, Bermúdez-Humarán LG, Smirnova N, Bergé M, Sulpice T, Lahtinen S, Ouwehand A, Langella P, Rautonen N, Sansonetti PJ, Burcelin R. Amar J, et al. Among authors: klopp p. EMBO Mol Med. 2011 Sep;3(9):559-72. doi: 10.1002/emmm.201100159. Epub 2011 Aug 3. EMBO Mol Med. 2011. PMID: 21735552 Free PMC article.
Metabolic adaptation to a high-fat diet is associated with a change in the gut microbiota.
Serino M, Luche E, Gres S, Baylac A, Bergé M, Cenac C, Waget A, Klopp P, Iacovoni J, Klopp C, Mariette J, Bouchez O, Lluch J, Ouarné F, Monsan P, Valet P, Roques C, Amar J, Bouloumié A, Théodorou V, Burcelin R. Serino M, et al. Among authors: klopp p. Gut. 2012 Apr;61(4):543-53. doi: 10.1136/gutjnl-2011-301012. Epub 2011 Nov 22. Gut. 2012. PMID: 22110050 Free PMC article.
Lixisenatide requires a functional gut-vagus nerve-brain axis to trigger insulin secretion in controls and type 2 diabetic mice.
Charpentier J, Waget A, Klopp P, Magnan C, Cruciani-Guglielmacci C, Lee SJ, Burcelin R, Grasset E. Charpentier J, et al. Among authors: klopp p. Am J Physiol Gastrointest Liver Physiol. 2018 Nov 1;315(5):G671-G684. doi: 10.1152/ajpgi.00348.2017. Epub 2018 Aug 2. Am J Physiol Gastrointest Liver Physiol. 2018. PMID: 30070580 Free article.
18 results