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Identification of a talin-binding site in the integrin beta(3) subunit distinct from the NPLY regulatory motif of post-ligand binding functions. The talin n-terminal head domain interacts with the membrane-proximal region of the beta(3) cytoplasmic tail.
Patil S, Jedsadayanmata A, Wencel-Drake JD, Wang W, Knezevic I, Lam SC. Patil S, et al. Among authors: knezevic i. J Biol Chem. 1999 Oct 1;274(40):28575-83. doi: 10.1074/jbc.274.40.28575. J Biol Chem. 1999. PMID: 10497223 Free article.
Ablation of p21-activated kinase-1 in mice promotes isoproterenol-induced cardiac hypertrophy in association with activation of Erk1/2 and inhibition of protein phosphatase 2A.
Taglieri DM, Monasky MM, Knezevic I, Sheehan KA, Lei M, Wang X, Chernoff J, Wolska BM, Ke Y, Solaro RJ. Taglieri DM, et al. Among authors: knezevic i. J Mol Cell Cardiol. 2011 Dec;51(6):988-96. doi: 10.1016/j.yjmcc.2011.09.016. Epub 2011 Sep 24. J Mol Cell Cardiol. 2011. PMID: 21971074 Free PMC article.
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