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Study of a mechanism responsible for potential antidepressant activity of EMD 386088, a 5-HT6 partial agonist in rats.
Jastrzębska-Więsek M, Siwek A, Partyka A, Antkiewicz-Michaluk L, Michaluk J, Romańska I, Kołaczkowski M, Wesołowska A. Jastrzębska-Więsek M, et al. Among authors: kolaczkowski m. Naunyn Schmiedebergs Arch Pharmacol. 2016 Aug;389(8):839-49. doi: 10.1007/s00210-016-1245-3. Epub 2016 Apr 23. Naunyn Schmiedebergs Arch Pharmacol. 2016. PMID: 27106213 Free PMC article.
Synthesis and pharmacological evaluation of new 5-(cyclo)alkyl-5-phenyl- and 5-spiroimidazolidine-2,4-dione derivatives. Novel 5-HT1A receptor agonist with potential antidepressant and anxiolytic activity.
Czopek A, Byrtus H, Kołaczkowski M, Pawłowski M, Dybała M, Nowak G, Tatarczyńska E, Wesołowska A, Chojnacka-Wójcik E. Czopek A, et al. Among authors: kolaczkowski m. Eur J Med Chem. 2010 Apr;45(4):1295-303. doi: 10.1016/j.ejmech.2009.11.053. Epub 2009 Dec 6. Eur J Med Chem. 2010. PMID: 20060623
Antipsychotic, antidepressant, and cognitive-impairment properties of antipsychotics: rat profile and implications for behavioral and psychological symptoms of dementia.
Kołaczkowski M, Mierzejewski P, Bienkowski P, Wesołowska A, Newman-Tancredi A. Kołaczkowski M, et al. Naunyn Schmiedebergs Arch Pharmacol. 2014 Jun;387(6):545-57. doi: 10.1007/s00210-014-0966-4. Epub 2014 Mar 6. Naunyn Schmiedebergs Arch Pharmacol. 2014. PMID: 24599316 Free PMC article.
Pharmacological evaluation of the anxiolytic-like effects of EMD 386088, a partial 5-HT6 receptor agonist, in the rat elevated plus-maze and Vogel conflict tests.
Jastrzębska-Więsek M, Siwek A, Partyka A, Kubacka M, Mogilski S, Wasik A, Kołaczkowski M, Wesołowska A. Jastrzębska-Więsek M, et al. Among authors: kolaczkowski m. Neuropharmacology. 2014 Oct;85:253-62. doi: 10.1016/j.neuropharm.2014.05.036. Epub 2014 Jun 4. Neuropharmacology. 2014. PMID: 24905144
137 results