Koek W - Search Results

1

F 11440, a potent, selective, high efficacy 5-HT1A receptor agonist with marked anxiolytic and antidepressant potential.

Koek W, Patoiseau JF, Assié MB, Cosi C, Kleven MS, Dupont-Passelaigue E, Carilla-Durand E, Palmier C, Valentin JP, John G, Pauwels PJ, Tarayre JP, Colpaert FC. Koek W, et al. J Pharmacol Exp Ther. 1998 Oct;287(1):266-83. J Pharmacol Exp Ther. 1998. PMID: 9765347

2

5-HT1A receptor activation and anti-cataleptic effects: high-efficacy agonists maximally inhibit haloperidol-induced catalepsy.

Prinssen EP, Colpaert FC, Koek W. Prinssen EP, et al. Among authors: koek w. Eur J Pharmacol. 2002 Oct 25;453(2-3):217-21. doi: 10.1016/s0014-2999(02)02430-5. Eur J Pharmacol. 2002. PMID: 12398907

3

Dual, hyperalgesic, and analgesic effects of the high-efficacy 5-hydroxytryptamine 1A (5-HT1A) agonist F 13640 [(3-chloro-4-fluoro-phenyl)-[4-fluoro-4-{[(5-methyl-pyridin-2-ylmethyl)-amino]-methyl}piperidin-1-yl]methanone, fumaric acid salt]: relationship with 5-HT1A receptor occupancy and kinetic parameters.

Bardin L, Assié MB, Pélissou M, Royer-Urios I, Newman-Tancredi A, Ribet JP, Sautel F, Koek W, Colpaert FC. Bardin L, et al. Among authors: koek w. J Pharmacol Exp Ther. 2005 Mar;312(3):1034-42. doi: 10.1124/jpet.104.077669. Epub 2004 Nov 4. J Pharmacol Exp Ther. 2005. PMID: 15528450

4

F15599, a highly selective post-synaptic 5-HT(1A) receptor agonist: in-vivo profile in behavioural models of antidepressant and serotonergic activity.

Assié MB, Bardin L, Auclair AL, Carilla-Durand E, Depoortère R, Koek W, Kleven MS, Colpaert F, Vacher B, Newman-Tancredi A. Assié MB, et al. Among authors: koek w. Int J Neuropsychopharmacol. 2010 Nov;13(10):1285-98. doi: 10.1017/S1461145709991222. Epub 2010 Jan 11. Int J Neuropsychopharmacol. 2010. PMID: 20059805 Free article.

5

Role of 5-HT1A receptors in the ability of mixed 5-HT1A receptor agonist/dopamine D2 receptor antagonists to inhibit methylphenidate-induced behaviors in rats.

Kleven M, Prinssen EP, Koek W. Kleven M, et al. Among authors: koek w. Eur J Pharmacol. 1996 Oct 10;313(1-2):25-34. doi: 10.1016/0014-2999(96)00498-0. Eur J Pharmacol. 1996. PMID: 8905325

6

Possible in vivo 5-HT reuptake blocking properties of 8-OH-DPAT assessed by measuring hippocampal extracellular 5-HT using microdialysis in rats.

Assié MB, Koek W. Assié MB, et al. Among authors: koek w. Br J Pharmacol. 1996 Nov;119(5):845-50. doi: 10.1111/j.1476-5381.1996.tb15749.x. Br J Pharmacol. 1996. PMID: 8922730 Free PMC article.

7

Effects of dopamine antagonists in a two-way active avoidance procedure in rats: interactions with 8-OH-DPAT, ritanserin, and prazosin.

Prinssen EP, Kleven MS, Koek W. Prinssen EP, et al. Among authors: koek w. Psychopharmacology (Berl). 1996 Nov;128(2):191-7. doi: 10.1007/s002130050124. Psychopharmacology (Berl). 1996. PMID: 8956380

8

Differential effects of direct and indirect dopamine agonists on eye blink rate in cynomolgus monkeys.

Kleven MS, Koek W. Kleven MS, et al. Among authors: koek w. J Pharmacol Exp Ther. 1996 Dec;279(3):1211-9. J Pharmacol Exp Ther. 1996. PMID: 8968343

9

Dopamine D2 receptors play a role in the (-)-apomorphine-like discriminative stimulus effects of (+)-PD 128907.

Kleven MS, Koek W. Kleven MS, et al. Among authors: koek w. Eur J Pharmacol. 1997 Feb 19;321(1):1-4. doi: 10.1016/s0014-2999(97)00002-2. Eur J Pharmacol. 1997. PMID: 9083778

10

Pharmacological characterization of in vivo properties of putative mixed 5-HT1A agonist/5-HT(2A/2C) antagonist anxiolytics. II. Drug discrimination and behavioral observation studies in rats.

Kleven MS, Assié MB, Koek W. Kleven MS, et al. Among authors: koek w. J Pharmacol Exp Ther. 1997 Aug;282(2):747-59. J Pharmacol Exp Ther. 1997. PMID: 9262338

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