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Trans-omic Analysis Reveals Selective Responses to Induced and Basal Insulin across Signaling, Transcriptional, and Metabolic Networks.
Kawata K, Hatano A, Yugi K, Kubota H, Sano T, Fujii M, Tomizawa Y, Kokaji T, Tanaka KY, Uda S, Suzuki Y, Matsumoto M, Nakayama KI, Saitoh K, Kato K, Ueno A, Ohishi M, Hirayama A, Soga T, Kuroda S. Kawata K, et al. Among authors: kokaji t. iScience. 2018 Sep 28;7:212-229. doi: 10.1016/j.isci.2018.07.022. Epub 2018 Sep 10. iScience. 2018. PMID: 30267682 Free PMC article.
Transomics analysis reveals allosteric and gene regulation axes for altered hepatic glucose-responsive metabolism in obesity.
Kokaji T, Hatano A, Ito Y, Yugi K, Eto M, Morita K, Ohno S, Fujii M, Hironaka KI, Egami R, Terakawa A, Tsuchiya T, Ozaki H, Inoue H, Uda S, Kubota H, Suzuki Y, Ikeda K, Arita M, Matsumoto M, Nakayama KI, Hirayama A, Soga T, Kuroda S. Kokaji T, et al. Sci Signal. 2020 Dec 1;13(660):eaaz1236. doi: 10.1126/scisignal.aaz1236. Sci Signal. 2020. PMID: 33262292
Trans-omic analysis reveals obesity-associated dysregulation of inter-organ metabolic cycles between the liver and skeletal muscle.
Egami R, Kokaji T, Hatano A, Yugi K, Eto M, Morita K, Ohno S, Fujii M, Hironaka KI, Uematsu S, Terakawa A, Bai Y, Pan Y, Tsuchiya T, Ozaki H, Inoue H, Uda S, Kubota H, Suzuki Y, Matsumoto M, Nakayama KI, Hirayama A, Soga T, Kuroda S. Egami R, et al. Among authors: kokaji t. iScience. 2021 Feb 20;24(3):102217. doi: 10.1016/j.isci.2021.102217. eCollection 2021 Mar 19. iScience. 2021. PMID: 33748705 Free PMC article.
Multi-omics-based label-free metabolic flux inference reveals obesity-associated dysregulatory mechanisms in liver glucose metabolism.
Uematsu S, Ohno S, Tanaka KY, Hatano A, Kokaji T, Ito Y, Kubota H, Hironaka KI, Suzuki Y, Matsumoto M, Nakayama KI, Hirayama A, Soga T, Kuroda S. Uematsu S, et al. Among authors: kokaji t. iScience. 2022 Feb 4;25(2):103787. doi: 10.1016/j.isci.2022.103787. eCollection 2022 Feb 18. iScience. 2022. PMID: 35243212 Free PMC article.
In vivo transomic analyses of glucose-responsive metabolism in skeletal muscle reveal core differences between the healthy and obese states.
Kokaji T, Eto M, Hatano A, Yugi K, Morita K, Ohno S, Fujii M, Hironaka KI, Ito Y, Egami R, Uematsu S, Terakawa A, Pan Y, Maehara H, Li D, Bai Y, Tsuchiya T, Ozaki H, Inoue H, Kubota H, Suzuki Y, Hirayama A, Soga T, Kuroda S. Kokaji T, et al. Sci Rep. 2022 Aug 12;12(1):13719. doi: 10.1038/s41598-022-17964-9. Sci Rep. 2022. PMID: 35962137 Free PMC article.
22 results