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Preclinical pharmacokinetics, biodistribution, radiation dosimetry and toxicity studies required for regulatory approval of a phase I clinical trial with (111)In-CP04 in medullary thyroid carcinoma patients.
Maina T, Konijnenberg MW, KolencPeitl P, Garnuszek P, Nock BA, Kaloudi A, Kroselj M, Zaletel K, Maecke H, Mansi R, Erba P, von Guggenberg E, Hubalewska-Dydejczyk A, Mikolajczak R, Decristoforo C. Maina T, et al. Eur J Pharm Sci. 2016 Aug 25;91:236-42. doi: 10.1016/j.ejps.2016.05.011. Epub 2016 May 14. Eur J Pharm Sci. 2016. PMID: 27185299 Free PMC article.
From preclinical development to clinical application: Kit formulation for radiolabelling the minigastrin analogue CP04 with In-111 for a first-in-human clinical trial.
Pawlak D, Rangger C, Kolenc Peitl P, Garnuszek P, Maurin M, Ihli L, Kroselj M, Maina T, Maecke H, Erba P, Kremser L, Hubalewska-Dydejczyk A, Mikołajczak R, Decristoforo C. Pawlak D, et al. Among authors: kolenc peitl p. Eur J Pharm Sci. 2016 Mar 31;85:1-9. doi: 10.1016/j.ejps.2016.01.023. Epub 2016 Jan 27. Eur J Pharm Sci. 2016. PMID: 26826279 Free PMC article.
Selection of the First 99mTc-Labelled Somatostatin Receptor Subtype 2 Antagonist for Clinical Translation-Preclinical Assessment of Two Optimized Candidates.
Fani M, Weingaertner V, Kolenc Peitl P, Mansi R, Gaonkar RH, Garnuszek P, Mikolajczak R, Novak D, Simoncic U, Hubalewska-Dydejczyk A, Rangger C, Kaeopookum P, Decristoforo C. Fani M, et al. Among authors: kolenc peitl p. Pharmaceuticals (Basel). 2020 Dec 28;14(1):19. doi: 10.3390/ph14010019. Pharmaceuticals (Basel). 2020. PMID: 33379299 Free PMC article.
CCK2R antagonists: from SAR to clinical trials.
Novak D, Anderluh M, Kolenc Peitl P. Novak D, et al. Among authors: kolenc peitl p. Drug Discov Today. 2020 Aug;25(8):1322-1336. doi: 10.1016/j.drudis.2020.05.008. Epub 2020 May 18. Drug Discov Today. 2020. PMID: 32439608 Review.
15 results