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NMT1 and NMT2 are lysine myristoyltransferases regulating the ARF6 GTPase cycle.
Kosciuk T, Price IR, Zhang X, Zhu C, Johnson KN, Zhang S, Halaby SL, Komaniecki GP, Yang M, DeHart CJ, Thomas PM, Kelleher NL, Fromme JC, Lin H. Kosciuk T, et al. Among authors: komaniecki gp. Nat Commun. 2020 Feb 26;11(1):1067. doi: 10.1038/s41467-020-14893-x. Nat Commun. 2020. PMID: 32103017 Free PMC article.
A STAT3 palmitoylation cycle promotes TH17 differentiation and colitis.
Zhang M, Zhou L, Xu Y, Yang M, Xu Y, Komaniecki GP, Kosciuk T, Chen X, Lu X, Zou X, Linder ME, Lin H. Zhang M, et al. Among authors: komaniecki gp. Nature. 2020 Oct;586(7829):434-439. doi: 10.1038/s41586-020-2799-2. Epub 2020 Oct 7. Nature. 2020. PMID: 33029007 Free PMC article.
Development of a NanoBRET assay to validate inhibitors of Sirt2-mediated lysine deacetylation and defatty-acylation that block prostate cancer cell migration.
Vogelmann A, Schiedel M, Wössner N, Merz A, Herp D, Hammelmann S, Colcerasa A, Komaniecki G, Hong JY, Sum M, Metzger E, Neuwirt E, Zhang L, Einsle O, Groß O, Schüle R, Lin H, Sippl W, Jung M. Vogelmann A, et al. RSC Chem Biol. 2022 Mar 1;3(4):468-485. doi: 10.1039/d1cb00244a. eCollection 2022 Apr 6. RSC Chem Biol. 2022. PMID: 35441145 Free PMC article.