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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 1
2003 3
2004 4
2005 5
2006 12
2007 22
2008 10
2009 6
2010 5
2011 7
2012 4
2013 5
2014 8
2015 8
2016 11
2017 5
2018 12
2019 15
2020 18
2021 9
2022 19
2023 14
2024 3

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185 results

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Page 1
Targeting replication stress in cancer therapy.
da Costa AABA, Chowdhury D, Shapiro GI, D'Andrea AD, Konstantinopoulos PA. da Costa AABA, et al. Among authors: konstantinopoulos pa. Nat Rev Drug Discov. 2023 Jan;22(1):38-58. doi: 10.1038/s41573-022-00558-5. Epub 2022 Oct 6. Nat Rev Drug Discov. 2023. PMID: 36202931 Review.
A single-cell landscape of high-grade serous ovarian cancer.
Izar B, Tirosh I, Stover EH, Wakiro I, Cuoco MS, Alter I, Rodman C, Leeson R, Su MJ, Shah P, Iwanicki M, Walker SR, Kanodia A, Melms JC, Mei S, Lin JR, Porter CBM, Slyper M, Waldman J, Jerby-Arnon L, Ashenberg O, Brinker TJ, Mills C, Rogava M, Vigneau S, Sorger PK, Garraway LA, Konstantinopoulos PA, Liu JF, Matulonis U, Johnson BE, Rozenblatt-Rosen O, Rotem A, Regev A. Izar B, et al. Among authors: konstantinopoulos pa. Nat Med. 2020 Aug;26(8):1271-1279. doi: 10.1038/s41591-020-0926-0. Epub 2020 Jun 22. Nat Med. 2020. PMID: 32572264 Free PMC article.
Homologous-recombination-deficient tumours are dependent on Polθ-mediated repair.
Ceccaldi R, Liu JC, Amunugama R, Hajdu I, Primack B, Petalcorin MI, O'Connor KW, Konstantinopoulos PA, Elledge SJ, Boulton SJ, Yusufzai T, D'Andrea AD. Ceccaldi R, et al. Among authors: konstantinopoulos pa. Nature. 2015 Feb 12;518(7538):258-62. doi: 10.1038/nature14184. Epub 2015 Feb 2. Nature. 2015. PMID: 25642963 Free PMC article.
STING agonism reprograms tumor-associated macrophages and overcomes resistance to PARP inhibition in BRCA1-deficient models of breast cancer.
Wang Q, Bergholz JS, Ding L, Lin Z, Kabraji SK, Hughes ME, He X, Xie S, Jiang T, Wang W, Zoeller JJ, Kim HJ, Roberts TM, Konstantinopoulos PA, Matulonis UA, Dillon DA, Winer EP, Lin NU, Zhao JJ. Wang Q, et al. Among authors: konstantinopoulos pa. Nat Commun. 2022 May 31;13(1):3022. doi: 10.1038/s41467-022-30568-1. Nat Commun. 2022. PMID: 35641483 Free PMC article.
Replication fork stability confers chemoresistance in BRCA-deficient cells.
Ray Chaudhuri A, Callen E, Ding X, Gogola E, Duarte AA, Lee JE, Wong N, Lafarga V, Calvo JA, Panzarino NJ, John S, Day A, Crespo AV, Shen B, Starnes LM, de Ruiter JR, Daniel JA, Konstantinopoulos PA, Cortez D, Cantor SB, Fernandez-Capetillo O, Ge K, Jonkers J, Rottenberg S, Sharan SK, Nussenzweig A. Ray Chaudhuri A, et al. Among authors: konstantinopoulos pa. Nature. 2016 Jul 21;535(7612):382-7. doi: 10.1038/nature18325. Nature. 2016. PMID: 27443740 Free PMC article.
Single-cell tumor-immune microenvironment of BRCA1/2 mutated high-grade serous ovarian cancer.
Launonen IM, Lyytikäinen N, Casado J, Anttila EA, Szabó A, Haltia UM, Jacobson CA, Lin JR, Maliga Z, Howitt BE, Strickland KC, Santagata S, Elias K, D'Andrea AD, Konstantinopoulos PA, Sorger PK, Färkkilä A. Launonen IM, et al. Among authors: konstantinopoulos pa. Nat Commun. 2022 Feb 11;13(1):835. doi: 10.1038/s41467-022-28389-3. Nat Commun. 2022. PMID: 35149709 Free PMC article.
PARP Inhibition Elicits STING-Dependent Antitumor Immunity in Brca1-Deficient Ovarian Cancer.
Ding L, Kim HJ, Wang Q, Kearns M, Jiang T, Ohlson CE, Li BB, Xie S, Liu JF, Stover EH, Howitt BE, Bronson RT, Lazo S, Roberts TM, Freeman GJ, Konstantinopoulos PA, Matulonis UA, Zhao JJ. Ding L, et al. Among authors: konstantinopoulos pa. Cell Rep. 2018 Dec 11;25(11):2972-2980.e5. doi: 10.1016/j.celrep.2018.11.054. Cell Rep. 2018. PMID: 30540933 Free PMC article.
STING agonism overcomes STAT3-mediated immunosuppression and adaptive resistance to PARP inhibition in ovarian cancer.
Ding L, Wang Q, Martincuks A, Kearns MJ, Jiang T, Lin Z, Cheng X, Qian C, Xie S, Kim HJ, Launonen IM, Färkkilä A, Roberts TM, Freeman GJ, Liu JF, Konstantinopoulos PA, Matulonis U, Yu H, Zhao JJ. Ding L, et al. Among authors: konstantinopoulos pa. J Immunother Cancer. 2023 Jan;11(1):e005627. doi: 10.1136/jitc-2022-005627. J Immunother Cancer. 2023. PMID: 36609487 Free PMC article.
185 results