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5-Formylcytosine to cytosine conversion by C-C bond cleavage in vivo.
Iwan K, Rahimoff R, Kirchner A, Spada F, Schröder AS, Kosmatchev O, Ferizaj S, Steinbacher J, Parsa E, Müller M, Carell T. Iwan K, et al. Among authors: kosmatchev o. Nat Chem Biol. 2018 Jan;14(1):72-78. doi: 10.1038/nchembio.2531. Epub 2017 Nov 27. Nat Chem Biol. 2018. PMID: 29176672
Tet oxidizes thymine to 5-hydroxymethyluracil in mouse embryonic stem cell DNA.
Pfaffeneder T, Spada F, Wagner M, Brandmayr C, Laube SK, Eisen D, Truss M, Steinbacher J, Hackner B, Kotljarova O, Schuermann D, Michalakis S, Kosmatchev O, Schiesser S, Steigenberger B, Raddaoui N, Kashiwazaki G, Müller U, Spruijt CG, Vermeulen M, Leonhardt H, Schär P, Müller M, Carell T. Pfaffeneder T, et al. Among authors: kosmatchev o. Nat Chem Biol. 2014 Jul;10(7):574-81. doi: 10.1038/nchembio.1532. Epub 2014 May 18. Nat Chem Biol. 2014. PMID: 24838012
Active turnover of genomic methylcytosine in pluripotent cells.
Spada F, Schiffers S, Kirchner A, Zhang Y, Arista G, Kosmatchev O, Korytiakova E, Rahimoff R, Ebert C, Carell T. Spada F, et al. Among authors: kosmatchev o. Nat Chem Biol. 2020 Dec;16(12):1411-1419. doi: 10.1038/s41589-020-0621-y. Epub 2020 Aug 10. Nat Chem Biol. 2020. PMID: 32778844