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Page 1
Deletion of skeletal muscle Akt1/2 causes osteosarcopenia and reduces lifespan in mice.
Sasako T, Umehara T, Soeda K, Kaneko K, Suzuki M, Kobayashi N, Okazaki Y, Tamura-Nakano M, Chiba T, Accili D, Kahn CR, Noda T, Asahara H, Yamauchi T, Kadowaki T, Ueki K. Sasako T, et al. Among authors: soeda k. Nat Commun. 2022 Oct 5;13(1):5655. doi: 10.1038/s41467-022-33008-2. Nat Commun. 2022. PMID: 36198696 Free PMC article.
Gut insulin action protects from hepatocarcinogenesis in diabetic mice comorbid with nonalcoholic steatohepatitis.
Soeda K, Sasako T, Enooku K, Kubota N, Kobayashi N, Ikushima YM, Awazawa M, Bouchi R, Toda G, Yamada T, Nakatsuka T, Tateishi R, Kakiuchi M, Yamamoto S, Tatsuno K, Atarashi K, Suda W, Honda K, Aburatani H, Yamauchi T, Fujishiro M, Noda T, Koike K, Kadowaki T, Ueki K. Soeda K, et al. Nat Commun. 2023 Oct 18;14(1):6584. doi: 10.1038/s41467-023-42334-y. Nat Commun. 2023. PMID: 37852976 Free PMC article.
An antisense transcript transcribed from Irs2 locus contributes to the pathogenesis of hepatic steatosis in insulin resistance.
Matsushita M, Awazawa M, Kobayashi N, Ikushima YM, Soeda K, Tamura-Nakano M, Muratani M, Kobayashi K, Blüher M, Brüning JC, Ueki K. Matsushita M, et al. Among authors: soeda k. Cell Chem Biol. 2022 Apr 21;29(4):680-689.e6. doi: 10.1016/j.chembiol.2021.12.008. Epub 2022 Jan 4. Cell Chem Biol. 2022. PMID: 34986326 Free article.
Insulin- and Lipopolysaccharide-Mediated Signaling in Adipose Tissue Macrophages Regulates Postprandial Glycemia through Akt-mTOR Activation.
Toda G, Soeda K, Okazaki Y, Kobayashi N, Masuda Y, Arakawa N, Suwanai H, Masamoto Y, Izumida Y, Kamei N, Sasako T, Suzuki R, Kubota T, Kubota N, Kurokawa M, Tobe K, Noda T, Honda K, Accili D, Yamauchi T, Kadowaki T, Ueki K. Toda G, et al. Among authors: soeda k. Mol Cell. 2020 Jul 2;79(1):43-53.e4. doi: 10.1016/j.molcel.2020.04.033. Epub 2020 May 27. Mol Cell. 2020. PMID: 32464093 Free article.
MEK/ERK Signaling in β-Cells Bifunctionally Regulates β-Cell Mass and Glucose-Stimulated Insulin Secretion Response to Maintain Glucose Homeostasis.
Ikushima YM, Awazawa M, Kobayashi N, Osonoi S, Takemiya S, Kobayashi H, Suwanai H, Morimoto Y, Soeda K, Adachi J, Muratani M, Charron J, Mizukami H, Takahashi N, Ueki K. Ikushima YM, et al. Among authors: soeda k. Diabetes. 2021 Jul;70(7):1519-1535. doi: 10.2337/db20-1295. Epub 2021 Apr 27. Diabetes. 2021. PMID: 33906910