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Patient-specific iPSCs carrying an SFTPC mutation reveal the intrinsic alveolar epithelial dysfunction at the inception of interstitial lung disease.
Alysandratos KD, Russo SJ, Petcherski A, Taddeo EP, Acín-Pérez R, Villacorta-Martin C, Jean JC, Mulugeta S, Rodriguez LR, Blum BC, Hekman RM, Hix OT, Minakin K, Vedaie M, Kook S, Tilston-Lunel AM, Varelas X, Wambach JA, Cole FS, Hamvas A, Young LR, Liesa M, Emili A, Guttentag SH, Shirihai OS, Beers MF, Kotton DN. Alysandratos KD, et al. Among authors: kotton dn. Cell Rep. 2021 Aug 31;36(9):109636. doi: 10.1016/j.celrep.2021.109636. Cell Rep. 2021. PMID: 34469722 Free PMC article.
Failure of bone marrow to reconstitute lung epithelium.
Kotton DN, Fabian AJ, Mulligan RC. Kotton DN, et al. Am J Respir Cell Mol Biol. 2005 Oct;33(4):328-34. doi: 10.1165/rcmb.2005-0175RC. Epub 2005 Jun 16. Am J Respir Cell Mol Biol. 2005. PMID: 15961722 Free PMC article.
Lung stem cells.
Kotton DN, Fine A. Kotton DN, et al. Cell Tissue Res. 2008 Jan;331(1):145-56. doi: 10.1007/s00441-007-0479-2. Epub 2007 Sep 6. Cell Tissue Res. 2008. PMID: 17805578 Review.
Generation of transgene-free lung disease-specific human induced pluripotent stem cells using a single excisable lentiviral stem cell cassette.
Somers A, Jean JC, Sommer CA, Omari A, Ford CC, Mills JA, Ying L, Sommer AG, Jean JM, Smith BW, Lafyatis R, Demierre MF, Weiss DJ, French DL, Gadue P, Murphy GJ, Mostoslavsky G, Kotton DN. Somers A, et al. Among authors: kotton dn. Stem Cells. 2010 Oct;28(10):1728-40. doi: 10.1002/stem.495. Stem Cells. 2010. PMID: 20715179 Free PMC article.
Efficient derivation of purified lung and thyroid progenitors from embryonic stem cells.
Longmire TA, Ikonomou L, Hawkins F, Christodoulou C, Cao Y, Jean JC, Kwok LW, Mou H, Rajagopal J, Shen SS, Dowton AA, Serra M, Weiss DJ, Green MD, Snoeck HW, Ramirez MI, Kotton DN. Longmire TA, et al. Among authors: kotton dn. Cell Stem Cell. 2012 Apr 6;10(4):398-411. doi: 10.1016/j.stem.2012.01.019. Cell Stem Cell. 2012. PMID: 22482505 Free PMC article.
Diffuse lung disease in children: summary of a scientific conference.
Hamvas A, Deterding R, Balch WE, Schwartz DA, Albertine KH, Whitsett JA, Cardoso WV, Kotton DN, Kourembanas S, Hagood JS. Hamvas A, et al. Among authors: kotton dn. Pediatr Pulmonol. 2014 Apr;49(4):400-9. doi: 10.1002/ppul.22805. Epub 2013 Jun 24. Pediatr Pulmonol. 2014. PMID: 23798474 Free PMC article.
Clonal genetic and hematopoietic heterogeneity among human-induced pluripotent stem cell lines.
Mills JA, Wang K, Paluru P, Ying L, Lu L, Galvão AM, Xu D, Yao Y, Sullivan SK, Sullivan LM, Mac H, Omari A, Jean JC, Shen S, Gower A, Spira A, Mostoslavsky G, Kotton DN, French DL, Weiss MJ, Gadue P. Mills JA, et al. Among authors: kotton dn. Blood. 2013 Sep 19;122(12):2047-51. doi: 10.1182/blood-2013-02-484444. Epub 2013 Aug 12. Blood. 2013. PMID: 23940280 Free PMC article.
Induced pluripotent stem cell modeling of multisystemic, hereditary transthyretin amyloidosis.
Leung A, Nah SK, Reid W, Ebata A, Koch CM, Monti S, Genereux JC, Wiseman RL, Wolozin B, Connors LH, Berk JL, Seldin DC, Mostoslavsky G, Kotton DN, Murphy GJ. Leung A, et al. Among authors: kotton dn. Stem Cell Reports. 2013 Oct 31;1(5):451-63. doi: 10.1016/j.stemcr.2013.10.003. eCollection 2013. Stem Cell Reports. 2013. PMID: 24286032 Free PMC article.
Identification of a common Wnt-associated genetic signature across multiple cell types in pulmonary arterial hypertension.
West JD, Austin ED, Gaskill C, Marriott S, Baskir R, Bilousova G, Jean JC, Hemnes AR, Menon S, Bloodworth NC, Fessel JP, Kropski JA, Irwin D, Ware LB, Wheeler L, Hong CC, Meyrick B, Loyd JE, Bowman AB, Ess KC, Klemm DJ, Young PP, Merryman WD, Kotton D, Majka SM. West JD, et al. Am J Physiol Cell Physiol. 2014 Sep 1;307(5):C415-30. doi: 10.1152/ajpcell.00057.2014. Epub 2014 May 28. Am J Physiol Cell Physiol. 2014. PMID: 24871858 Free PMC article.
162 results