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Nonpyrogenic Molecular Adjuvants Based on norAbu-Muramyldipeptide and norAbu-Glucosaminyl Muramyldipeptide: Synthesis, Molecular Mechanisms of Action, and Biological Activities in Vitro and in Vivo.
Effenberg R, Turánek Knötigová P, Zyka D, Čelechovská H, Mašek J, Bartheldyová E, Hubatka F, Koudelka Š, Lukáč R, Kovalová A, Šaman D, Křupka M, Barkocziova L, Kosztyu P, Šebela M, Drož L, Hučko M, Kanásová M, Miller AD, Raška M, Ledvina M, Turánek J. Effenberg R, et al. Among authors: kovalova a. J Med Chem. 2017 Sep 28;60(18):7745-7763. doi: 10.1021/acs.jmedchem.7b00593. Epub 2017 Sep 8. J Med Chem. 2017. PMID: 28829599
Synthetic N-acetyl-D-glucosamine based fully branched tetrasaccharide, a mimetic of the endogenous ligand for CD69, activates CD69+ killer lymphocytes upon dimerization via a hydrophilic flexible linker.
Kovalová A, Ledvina M, Saman D, Zyka D, Kubícková M, Zídek L, Sklenár V, Pompach P, Kavan D, Bílý J, Vanek O, Kubínková Z, Libigerová M, Ivanová L, Antolíková M, Mrázek H, Rozbeský D, Hofbauerová K, Kren V, Bezouska K. Kovalová A, et al. J Med Chem. 2010 May 27;53(10):4050-65. doi: 10.1021/jm100055b. J Med Chem. 2010. PMID: 20433142 Retracted.
Retraction: Synthetic N-acetyl-D-glucosamine based fully branched tetrasaccharide, a mimetic of the endogenous ligand for CD69, activates CD69⁺ killer lymphocytes upon dimerization via a hydrophilic flexible linker. Journal of Medicinal Chemistry 2010, 53, 4050-65.
Kovalová A, Ledvina M, Saman D, Zyka D, Kubíčková M, Zídek L, Sklenář V, Pompach P, Kavan D, Bílý J, Vaněk O, Kubínková Z, Libigerová M, Ivanová L, Antolíková M, Mrázek H, Rozbeský D, Hofbauerová K, Křen V, Bezouška K. Kovalová A, et al. J Med Chem. 2014 Jun 26;57(12):5477. doi: 10.1021/jm5007726. Epub 2014 Jun 5. J Med Chem. 2014. PMID: 24899138 No abstract available.
Molecular adjuvants based on nonpyrogenic lipophilic derivatives of norAbuMDP/GMDP formulated in nanoliposomes: stimulation of innate and adaptive immunity.
Knotigová PT, Zyka D, Mašek J, Kovalová A, Křupka M, Bartheldyová E, Kulich P, Koudelka Š, Lukáč R, Kauerová Z, Vacek A, Horynová MS, Kozubík A, Miller AD, Fekete L, Kratochvílová I, Ježek J, Ledvina M, Raška M, Turánek J. Knotigová PT, et al. Among authors: kovalova a. Pharm Res. 2015 Apr;32(4):1186-99. doi: 10.1007/s11095-014-1516-y. Epub 2015 Jan 30. Pharm Res. 2015. PMID: 25630814
Detection of Murine Herpesvirus 68 (MHV-68) in Dermacentor reticulatus Ticks.
Kúdelová M, Belvončíková P, Vrbová M, Kovaľová A, Štibrániová I, Kocáková P, Slovák M, Špitalská E, Lapuníková B, Matúšková R, Šupolíková M. Kúdelová M, et al. Among authors: kovalova a. Microb Ecol. 2015 Oct;70(3):785-94. doi: 10.1007/s00248-015-0622-7. Epub 2015 May 8. Microb Ecol. 2015. PMID: 25947097