Koymans KJ - Search Results

1

Bovine Staphylococcus aureus Secretes the Leukocidin LukMF' To Kill Migrating Neutrophils through CCR1.

Vrieling M, Koymans KJ, Heesterbeek DA, Aerts PC, Rutten VP, de Haas CJ, van Kessel KP, Koets AP, Nijland R, van Strijp JA. Vrieling M, et al. Among authors: koymans kj. mBio. 2015 Jun 4;6(3):e00335. doi: 10.1128/mBio.00335-15. mBio. 2015. PMID: 26045537 Free PMC article.

2

LukMF' is the major secreted leukocidin of bovine Staphylococcus aureus and is produced in vivo during bovine mastitis.

Vrieling M, Boerhout EM, van Wigcheren GF, Koymans KJ, Mols-Vorstermans TG, de Haas CJ, Aerts PC, Daemen IJ, van Kessel KP, Koets AP, Rutten VP, Nuijten PJ, van Strijp JA, Benedictus L. Vrieling M, et al. Among authors: koymans kj. Sci Rep. 2016 Nov 25;6:37759. doi: 10.1038/srep37759. Sci Rep. 2016. PMID: 27886237 Free PMC article.

3

Structural basis for inhibition of TLR2 by staphylococcal superantigen-like protein 3 (SSL3).

Koymans KJ, Feitsma LJ, Brondijk TH, Aerts PC, Lukkien E, Lössl P, van Kessel KP, de Haas CJ, van Strijp JA, Huizinga EG. Koymans KJ, et al. Proc Natl Acad Sci U S A. 2015 Sep 1;112(35):11018-23. doi: 10.1073/pnas.1502026112. Epub 2015 Aug 17. Proc Natl Acad Sci U S A. 2015. PMID: 26283364 Free PMC article.

4

Staphylococcal Immune Evasion Proteins: Structure, Function, and Host Adaptation.

Koymans KJ, Vrieling M, Gorham RD Jr, van Strijp JAG. Koymans KJ, et al. Curr Top Microbiol Immunol. 2017;409:441-489. doi: 10.1007/82_2015_5017. Curr Top Microbiol Immunol. 2017. PMID: 26919864 Review.

5

Staphylococcal Superantigen-Like Protein 1 and 5 (SSL1 & SSL5) Limit Neutrophil Chemotaxis and Migration through MMP-Inhibition.

Koymans KJ, Bisschop A, Vughs MM, van Kessel KP, de Haas CJ, van Strijp JA. Koymans KJ, et al. Int J Mol Sci. 2016 Jul 5;17(7):1072. doi: 10.3390/ijms17071072. Int J Mol Sci. 2016. PMID: 27399672 Free PMC article.

6

The TLR2 Antagonist Staphylococcal Superantigen-Like Protein 3 Acts as a Virulence Factor to Promote Bacterial Pathogenicity in vivo.

Koymans KJ, Goldmann O, Karlsson CAQ, Sital W, Thänert R, Bisschop A, Vrieling M, Malmström J, van Kessel KPM, de Haas CJC, van Strijp JAG, Medina E. Koymans KJ, et al. J Innate Immun. 2017;9(6):561-573. doi: 10.1159/000479100. Epub 2017 Sep 1. J Innate Immun. 2017. PMID: 28858870 Free article.

7

Molecular basis determining species specificity for TLR2 inhibition by staphylococcal superantigen-like protein 3 (SSL3).

Koymans KJ, Feitsma LJ, Bisschop A, Huizinga EG, van Strijp JAG, de Haas CJC, McCarthy AJ. Koymans KJ, et al. Vet Res. 2018 Nov 28;49(1):115. doi: 10.1186/s13567-018-0609-8. Vet Res. 2018. PMID: 30486901 Free PMC article.

8

The fungal ligand chitin directly binds TLR2 and triggers inflammation dependent on oligomer size.

Fuchs K, Cardona Gloria Y, Wolz OO, Herster F, Sharma L, Dillen CA, Täumer C, Dickhöfer S, Bittner Z, Dang TM, Singh A, Haischer D, Schlöffel MA, Koymans KJ, Sanmuganantham T, Krach M, Roger T, Le Roy D, Schilling NA, Frauhammer F, Miller LS, Nürnberger T, LeibundGut-Landmann S, Gust AA, Macek B, Frank M, Gouttefangeas C, Dela Cruz CS, Hartl D, Weber AN. Fuchs K, et al. Among authors: koymans kj. EMBO Rep. 2018 Dec;19(12):e46065. doi: 10.15252/embr.201846065. Epub 2018 Oct 18. EMBO Rep. 2018. PMID: 30337494 Free PMC article.

9

CFTR-mutation specific applications of CFTR-directed monoclonal antibodies.

van Meegen MA, Terheggen SW, Koymans KJ, Vijftigschild LA, Dekkers JF, van der Ent CK, Beekman JM. van Meegen MA, et al. Among authors: koymans kj. J Cyst Fibros. 2013 Sep;12(5):487-96. doi: 10.1016/j.jcf.2012.12.005. Epub 2013 Jan 11. J Cyst Fibros. 2013. PMID: 23317763 Free article.

10

Apical CFTR expression in human nasal epithelium correlates with lung disease in cystic fibrosis.

van Meegen MA, Terheggen-Lagro SW, Koymans KJ, van der Ent CK, Beekman JM. van Meegen MA, et al. Among authors: koymans kj. PLoS One. 2013;8(3):e57617. doi: 10.1371/journal.pone.0057617. Epub 2013 Mar 6. PLoS One. 2013. PMID: 23483918 Free PMC article.

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