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Foreign DNA capture during CRISPR-Cas adaptive immunity.
Nuñez JK, Harrington LB, Kranzusch PJ, Engelman AN, Doudna JA. Nuñez JK, et al. Among authors: kranzusch pj. Nature. 2015 Nov 26;527(7579):535-8. doi: 10.1038/nature15760. Epub 2015 Oct 21. Nature. 2015. PMID: 26503043 Free PMC article.
Bacterial cGAS-like enzymes synthesize diverse nucleotide signals.
Whiteley AT, Eaglesham JB, de Oliveira Mann CC, Morehouse BR, Lowey B, Nieminen EA, Danilchanka O, King DS, Lee ASY, Mekalanos JJ, Kranzusch PJ. Whiteley AT, et al. Among authors: kranzusch pj. Nature. 2019 Mar;567(7747):194-199. doi: 10.1038/s41586-019-0953-5. Epub 2019 Feb 20. Nature. 2019. PMID: 30787435 Free PMC article.
Analysis of human cGAS activity and structure.
Zhou W, Whiteley AT, Kranzusch PJ. Zhou W, et al. Among authors: kranzusch pj. Methods Enzymol. 2019;625:13-40. doi: 10.1016/bs.mie.2019.04.012. Epub 2019 May 2. Methods Enzymol. 2019. PMID: 31455523
STING cyclic dinucleotide sensing originated in bacteria.
Morehouse BR, Govande AA, Millman A, Keszei AFA, Lowey B, Ofir G, Shao S, Sorek R, Kranzusch PJ. Morehouse BR, et al. Among authors: kranzusch pj. Nature. 2020 Oct;586(7829):429-433. doi: 10.1038/s41586-020-2719-5. Epub 2020 Sep 2. Nature. 2020. PMID: 32877915 Free PMC article.
cGAS-like receptors sense RNA and control 3'2'-cGAMP signalling in Drosophila.
Slavik KM, Morehouse BR, Ragucci AE, Zhou W, Ai X, Chen Y, Li L, Wei Z, Bähre H, König M, Seifert R, Lee ASY, Cai H, Imler JL, Kranzusch PJ. Slavik KM, et al. Among authors: kranzusch pj. Nature. 2021 Sep;597(7874):109-113. doi: 10.1038/s41586-021-03743-5. Epub 2021 Jul 14. Nature. 2021. PMID: 34261127 Free PMC article.
78 results