Krauss S - Search Results

1

Novel synthetic antagonists of canonical Wnt signaling inhibit colorectal cancer cell growth.

Waaler J, Machon O, von Kries JP, Wilson SR, Lundenes E, Wedlich D, Gradl D, Paulsen JE, Machonova O, Dembinski JL, Dinh H, Krauss S. Waaler J, et al. Among authors: krauss s. Cancer Res. 2011 Jan 1;71(1):197-205. doi: 10.1158/0008-5472.CAN-10-1282. Cancer Res. 2011. PMID: 21199802

2

A novel tankyrase inhibitor decreases canonical Wnt signaling in colon carcinoma cells and reduces tumor growth in conditional APC mutant mice.

Waaler J, Machon O, Tumova L, Dinh H, Korinek V, Wilson SR, Paulsen JE, Pedersen NM, Eide TJ, Machonova O, Gradl D, Voronkov A, von Kries JP, Krauss S. Waaler J, et al. Among authors: krauss s. Cancer Res. 2012 Jun 1;72(11):2822-32. doi: 10.1158/0008-5472.CAN-11-3336. Epub 2012 Mar 22. Cancer Res. 2012. PMID: 22440753

3

TANKYRASE Inhibition Enhances the Antiproliferative Effect of PI3K and EGFR Inhibition, Mutually Affecting β-CATENIN and AKT Signaling in Colorectal Cancer.

Solberg NT, Waaler J, Lund K, Mygland L, Olsen PA, Krauss S. Solberg NT, et al. Among authors: krauss s. Mol Cancer Res. 2018 Mar;16(3):543-553. doi: 10.1158/1541-7786.MCR-17-0362. Epub 2017 Dec 8. Mol Cancer Res. 2018. PMID: 29222171

4

Characterisation of the Wnt antagonists and their response to conditionally activated Wnt signalling in the developing mouse forebrain.

Diep DB, Hoen N, Backman M, Machon O, Krauss S. Diep DB, et al. Among authors: krauss s. Brain Res Dev Brain Res. 2004 Nov 25;153(2):261-70. doi: 10.1016/j.devbrainres.2004.09.008. Brain Res Dev Brain Res. 2004. PMID: 15527894

5

A dynamic gradient of Wnt signaling controls initiation of neurogenesis in the mammalian cortex and cellular specification in the hippocampus.

Machon O, Backman M, Machonova O, Kozmik Z, Vacik T, Andersen L, Krauss S. Machon O, et al. Among authors: krauss s. Dev Biol. 2007 Nov 1;311(1):223-37. doi: 10.1016/j.ydbio.2007.08.038. Epub 2007 Aug 28. Dev Biol. 2007. PMID: 17916349 Free article.

6

Effect of canonical Wnt inhibition in the neurogenic cortex, hippocampus, and premigratory dentate gyrus progenitor pool.

Solberg N, Machon O, Krauss S. Solberg N, et al. Among authors: krauss s. Dev Dyn. 2008 Jul;237(7):1799-811. doi: 10.1002/dvdy.21586. Dev Dyn. 2008. PMID: 18521945 Free article.

7

A novel synthetic smoothened antagonist transiently inhibits pancreatic adenocarcinoma xenografts in a mouse model.

Strand MF, Wilson SR, Dembinski JL, Holsworth DD, Khvat A, Okun I, Petersen D, Krauss S. Strand MF, et al. Among authors: krauss s. PLoS One. 2011;6(6):e19904. doi: 10.1371/journal.pone.0019904. Epub 2011 Jun 15. PLoS One. 2011. PMID: 21698280 Free PMC article.

8

Mouse Tcf3 represses canonical Wnt signaling by either competing for β-catenin binding or through occupation of DNA-binding sites.

Solberg N, Machon O, Machonova O, Krauss S. Solberg N, et al. Among authors: krauss s. Mol Cell Biochem. 2012 Jun;365(1-2):53-63. doi: 10.1007/s11010-012-1243-9. Epub 2012 Jan 22. Mol Cell Biochem. 2012. PMID: 22270545

9

Structural basis and SAR for G007-LK, a lead stage 1,2,4-triazole based specific tankyrase 1/2 inhibitor.

Voronkov A, Holsworth DD, Waaler J, Wilson SR, Ekblad B, Perdreau-Dahl H, Dinh H, Drewes G, Hopf C, Morth JP, Krauss S. Voronkov A, et al. Among authors: krauss s. J Med Chem. 2013 Apr 11;56(7):3012-23. doi: 10.1021/jm4000566. Epub 2013 Mar 29. J Med Chem. 2013. PMID: 23473363

10

A novel tankyrase small-molecule inhibitor suppresses APC mutation-driven colorectal tumor growth.

Lau T, Chan E, Callow M, Waaler J, Boggs J, Blake RA, Magnuson S, Sambrone A, Schutten M, Firestein R, Machon O, Korinek V, Choo E, Diaz D, Merchant M, Polakis P, Holsworth DD, Krauss S, Costa M. Lau T, et al. Among authors: krauss s. Cancer Res. 2013 May 15;73(10):3132-44. doi: 10.1158/0008-5472.CAN-12-4562. Epub 2013 Mar 28. Cancer Res. 2013. PMID: 23539443

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