Krishnan VG - Search Results

1

TORC1 regulates the transcriptional response to glucose and developmental cycle via the Tap42-Sit4-Rrd1/2 pathway in Saccharomyces cerevisiae.

Alfatah M, Wong JH, Krishnan VG, Lee YC, Sin QF, Goh CJH, Kong KW, Lee WT, Lewis J, Hoon S, Arumugam P. Alfatah M, et al. Among authors: krishnan vg. BMC Biol. 2021 May 6;19(1):95. doi: 10.1186/s12915-021-01030-3. BMC Biol. 2021. PMID: 33957926 Free PMC article.

2

BCL-xL/BCL2L1 is a critical anti-apoptotic protein that promotes the survival of differentiating pancreatic cells from human pluripotent stem cells.

Loo LSW, Soetedjo AAP, Lau HH, Ng NHJ, Ghosh S, Nguyen L, Krishnan VG, Choi H, Roca X, Hoon S, Teo AKK. Loo LSW, et al. Among authors: krishnan vg. Cell Death Dis. 2020 May 18;11(5):378. doi: 10.1038/s41419-020-2589-7. Cell Death Dis. 2020. PMID: 32424151 Free PMC article.

3

Decreased GLUT2 and glucose uptake contribute to insulin secretion defects in MODY3/HNF1A hiPSC-derived mutant β cells.

Low BSJ, Lim CS, Ding SSL, Tan YS, Ng NHJ, Krishnan VG, Ang SF, Neo CWY, Verma CS, Hoon S, Lim SC, Tai ES, Teo AKK. Low BSJ, et al. Among authors: krishnan vg. Nat Commun. 2021 May 25;12(1):3133. doi: 10.1038/s41467-021-22843-4. Nat Commun. 2021. PMID: 34035238 Free PMC article.

4

HNF4A Haploinsufficiency in MODY1 Abrogates Liver and Pancreas Differentiation from Patient-Derived Induced Pluripotent Stem Cells.

Ng NHJ, Jasmen JB, Lim CS, Lau HH, Krishnan VG, Kadiwala J, Kulkarni RN, Ræder H, Vallier L, Hoon S, Teo AKK. Ng NHJ, et al. Among authors: krishnan vg. iScience. 2019 Jun 28;16:192-205. doi: 10.1016/j.isci.2019.05.032. Epub 2019 May 27. iScience. 2019. PMID: 31195238 Free PMC article.

5

Bioinformatic tools for identifying disease gene and SNP candidates.

Mooney SD, Krishnan VG, Evani US. Mooney SD, et al. Among authors: krishnan vg. Methods Mol Biol. 2010;628:307-19. doi: 10.1007/978-1-60327-367-1_17. Methods Mol Biol. 2010. PMID: 20238089 Free PMC article. Review.

6

Predicting cancer drivers: are we there yet?

Krishnan VG, Ng PC. Krishnan VG, et al. Genome Med. 2012 Nov 26;4(11):88. doi: 10.1186/gm389. eCollection 2012. Genome Med. 2012. PMID: 23181697 Free PMC article.

7

Automated inference of molecular mechanisms of disease from amino acid substitutions.

Li B, Krishnan VG, Mort ME, Xin F, Kamati KK, Cooper DN, Mooney SD, Radivojac P. Li B, et al. Among authors: krishnan vg. Bioinformatics. 2009 Nov 1;25(21):2744-50. doi: 10.1093/bioinformatics/btp528. Epub 2009 Sep 3. Bioinformatics. 2009. PMID: 19734154 Free PMC article.

8

In silico functional profiling of human disease-associated and polymorphic amino acid substitutions.

Mort M, Evani US, Krishnan VG, Kamati KK, Baenziger PH, Bagchi A, Peters BJ, Sathyesh R, Li B, Sun Y, Xue B, Shah NH, Kann MG, Cooper DN, Radivojac P, Mooney SD. Mort M, et al. Among authors: krishnan vg. Hum Mutat. 2010 Mar;31(3):335-46. doi: 10.1002/humu.21192. Hum Mutat. 2010. PMID: 20052762 Free PMC article.

9

A comparative study of machine-learning methods to predict the effects of single nucleotide polymorphisms on protein function.

Krishnan VG, Westhead DR. Krishnan VG, et al. Bioinformatics. 2003 Nov 22;19(17):2199-209. doi: 10.1093/bioinformatics/btg297. Bioinformatics. 2003. PMID: 14630648

10

Whole-genome sequencing of asian lung cancers: second-hand smoke unlikely to be responsible for higher incidence of lung cancer among Asian never-smokers.

Krishnan VG, Ebert PJ, Ting JC, Lim E, Wong SS, Teo AS, Yue YG, Chua HH, Ma X, Loh GS, Lin Y, Tan JH, Yu K, Zhang S, Reinhard C, Tan DS, Peters BA, Lincoln SE, Ballinger DG, Laramie JM, Nilsen GB, Barber TD, Tan P, Hillmer AM, Ng PC. Krishnan VG, et al. Cancer Res. 2014 Nov 1;74(21):6071-81. doi: 10.1158/0008-5472.CAN-13-3195. Epub 2014 Sep 4. Cancer Res. 2014. PMID: 25189529

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