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Page 1
NFATc1 signaling drives chronic ER stress responses to promote NAFLD progression.
Latif MU, Schmidt GE, Mercan S, Rahman R, Gibhardt CS, Stejerean-Todoran I, Reutlinger K, Hessmann E, Singh SK, Moeed A, Rehman A, Butt UJ, Bohnenberger H, Stroebel P, Bremer SC, Neesse A, Bogeski I, Ellenrieder V. Latif MU, et al. Among authors: reutlinger k. Gut. 2022 Dec;71(12):2561-2573. doi: 10.1136/gutjnl-2021-325013. Epub 2022 Apr 1. Gut. 2022. PMID: 35365570 Free PMC article.
An NFATc1/SMAD3/cJUN Complex Restricted to SMAD4-Deficient Pancreatic Cancer Guides Rational Therapies.
Hasselluhn MC, Schlösser D, Versemann L, Schmidt GE, Ulisse M, Oschwald J, Zhang Z, Hamdan F, Xiao H, Kopp W, Spitalieri J, Kellner C, Schneider C, Reutlinger K, Nagarajan S, Steuber B, Sastra SA, Palermo CF, Appelhans J, Bohnenberger H, Todorovic J, Kostyuchek I, Ströbel P, Bockelmann A, König A, Ammer-Herrmenau C, Schmidleitner L, Kaulfuß S, Wollnik B, Hahn SA, Neesse A, Singh SK, Bastians H, Reichert M, Sax U, Olive KP, Johnsen SA, Schneider G, Ellenrieder V, Hessmann E. Hasselluhn MC, et al. Among authors: reutlinger k. Gastroenterology. 2024 Feb;166(2):298-312.e14. doi: 10.1053/j.gastro.2023.10.026. Epub 2023 Oct 31. Gastroenterology. 2024. PMID: 37913894
Chromatin-Independent Interplay of NFATc1 and EZH2 in Pancreatic Cancer.
Patil S, Forster T, Reutlinger K, Kopp W, Versemann L, Spitalieri J, Gaedcke J, Ströbel P, Singh SK, Ellenrieder V, Neesse A, Hessmann E. Patil S, et al. Among authors: reutlinger k. Cells. 2021 Dec 8;10(12):3463. doi: 10.3390/cells10123463. Cells. 2021. PMID: 34943970 Free PMC article.
NFAT-induced histone acetylation relay switch promotes c-Myc-dependent growth in pancreatic cancer cells.
Köenig A, Linhart T, Schlengemann K, Reutlinger K, Wegele J, Adler G, Singh G, Hofmann L, Kunsch S, Büch T, Schäfer E, Gress TM, Fernandez-Zapico ME, Ellenrieder V. Köenig A, et al. Among authors: reutlinger k. Gastroenterology. 2010 Mar;138(3):1189-99.e1-2. doi: 10.1053/j.gastro.2009.10.045. Epub 2009 Nov 6. Gastroenterology. 2010. PMID: 19900447 Free PMC article.
Disruption of a nuclear NFATc2 protein stabilization loop confers breast and pancreatic cancer growth suppression by zoledronic acid.
Singh SK, Baumgart S, Singh G, König AO, Reutlinger K, Hofbauer LC, Barth P, Gress TM, Lomberk G, Urrutia R, Fernandez-Zapico ME, Ellenrieder V. Singh SK, et al. Among authors: reutlinger k. J Biol Chem. 2011 Aug 19;286(33):28761-28771. doi: 10.1074/jbc.M110.197533. Epub 2011 May 31. J Biol Chem. 2011. PMID: 21628454 Free PMC article.
Sequential activation of NFAT and c-Myc transcription factors mediates the TGF-beta switch from a suppressor to a promoter of cancer cell proliferation.
Singh G, Singh SK, König A, Reutlinger K, Nye MD, Adhikary T, Eilers M, Gress TM, Fernandez-Zapico ME, Ellenrieder V. Singh G, et al. Among authors: reutlinger k. J Biol Chem. 2010 Aug 27;285(35):27241-27250. doi: 10.1074/jbc.M110.100438. Epub 2010 Jun 1. J Biol Chem. 2010. PMID: 20516082 Free PMC article.