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Compounds from an unbiased chemical screen reverse both ER-to-Golgi trafficking defects and mitochondrial dysfunction in Parkinson's disease models.
Su LJ, Auluck PK, Outeiro TF, Yeger-Lotem E, Kritzer JA, Tardiff DF, Strathearn KE, Liu F, Cao S, Hamamichi S, Hill KJ, Caldwell KA, Bell GW, Fraenkel E, Cooper AA, Caldwell GA, McCaffery JM, Rochet JC, Lindquist S. Su LJ, et al. Among authors: kritzer ja. Dis Model Mech. 2010 Mar-Apr;3(3-4):194-208. doi: 10.1242/dmm.004267. Epub 2009 Dec 28. Dis Model Mech. 2010. PMID: 20038714 Free PMC article.
Structured cyclic peptides that bind the EH domain of EHD1.
Kamens AJ, Eisert RJ, Corlin T, Baleja JD, Kritzer JA. Kamens AJ, et al. Among authors: kritzer ja. Biochemistry. 2014 Jul 29;53(29):4758-60. doi: 10.1021/bi500744q. Epub 2014 Jul 17. Biochemistry. 2014. PMID: 25014215 Free PMC article.
Designing convergent chemistry curricula.
Charkoudian LK, Sampson NS, Kumar K, Kritzer JA. Charkoudian LK, et al. Among authors: kritzer ja. Nat Chem Biol. 2016 May 18;12(6):382-6. doi: 10.1038/nchembio.2090. Nat Chem Biol. 2016. PMID: 27191640 No abstract available.
60 results