Krol ES - Search Results

1

The effect of diphenylethane side-chain substituents on dibenzocyclohexadiene formation and their inhibition of α-synuclein aggregation in vitro.

Bernardes G, Munir O, Krol ES. Bernardes G, et al. Among authors: krol es. Bioorg Med Chem. 2023 Jan 15;78:117147. doi: 10.1016/j.bmc.2022.117147. Epub 2022 Dec 26. Bioorg Med Chem. 2023. PMID: 36587551

2

Ring substitution influences oxidative cyclisation and reactive metabolite formation of nordihydroguaiaretic acid analogues.

Asiamah I, Hodgson HL, Maloney K, Allen KJ, Krol ES. Asiamah I, et al. Among authors: krol es. Bioorg Med Chem. 2015 Nov 1;23(21):7007-14. doi: 10.1016/j.bmc.2015.09.039. Epub 2015 Sep 25. Bioorg Med Chem. 2015. PMID: 26439661

3

Cyclized NDGA modifies dynamic α-synuclein monomers preventing aggregation and toxicity.

Daniels MJ, Nourse JB Jr, Kim H, Sainati V, Schiavina M, Murrali MG, Pan B, Ferrie JJ, Haney CM, Moons R, Gould NS, Natalello A, Grandori R, Sobott F, Petersson EJ, Rhoades E, Pierattelli R, Felli I, Uversky VN, Caldwell KA, Caldwell GA, Krol ES, Ischiropoulos H. Daniels MJ, et al. Among authors: krol es. Sci Rep. 2019 Feb 27;9(1):2937. doi: 10.1038/s41598-019-39480-z. Sci Rep. 2019. PMID: 30814575 Free PMC article.

4

An HPLC-UV validated bioanalytical method for measurement of in vitro phase 1 kinetics of α-synuclein binding bifunctional compounds.

Aigbogun OP, Nwabufo CK, Owens MN, Allen KJH, Lee JS, Phenix CP, Krol ES. Aigbogun OP, et al. Among authors: krol es. Xenobiotica. 2022 Aug;52(8):916-927. doi: 10.1080/00498254.2022.2140315. Xenobiotica. 2022. PMID: 36282181

5

In vitro hepatic metabolism of the natural product quebecol.

Bernardes G, Krol ES. Bernardes G, et al. Among authors: krol es. Xenobiotica. 2023 Jan;53(1):1-11. doi: 10.1080/00498254.2023.2180691. Epub 2023 Apr 18. Xenobiotica. 2023. PMID: 36976846

6

Oxidation of the lignan nordihydroguaiaretic acid.

Billinsky JL, Marcoux MR, Krol ES. Billinsky JL, et al. Among authors: krol es. Chem Res Toxicol. 2007 Sep;20(9):1352-8. doi: 10.1021/tx700205j. Epub 2007 Aug 3. Chem Res Toxicol. 2007. PMID: 17672511

7

Nordihydroguaiaretic acid autoxidation produces a schisandrin-like dibenzocyclooctadiene lignan.

Billinsky JL, Krol ES. Billinsky JL, et al. Among authors: krol es. J Nat Prod. 2008 Sep;71(9):1612-5. doi: 10.1021/np8001354. Epub 2008 Aug 2. J Nat Prod. 2008. PMID: 18672930

8

Novel Dimer Compounds That Bind α-Synuclein Can Rescue Cell Growth in a Yeast Model Overexpressing α-Synuclein. A Possible Prevention Strategy for Parkinson's Disease.

Kakish J, Allen KJ, Harkness TA, Krol ES, Lee JS. Kakish J, et al. Among authors: krol es. ACS Chem Neurosci. 2016 Dec 21;7(12):1671-1680. doi: 10.1021/acschemneuro.6b00209. Epub 2016 Oct 7. ACS Chem Neurosci. 2016. PMID: 27673434

9

Employing in vitro metabolism to guide design of F-labelled PET probes of novel α-synuclein binding bifunctional compounds.

Nwabufo CK, Aigbogun OP, Allen KJH, Owens MN, Lee JS, Phenix CP, Krol ES. Nwabufo CK, et al. Among authors: krol es. Xenobiotica. 2021 Aug;51(8):885-900. doi: 10.1080/00498254.2021.1943566. Epub 2021 Jun 30. Xenobiotica. 2021. PMID: 34187286

10

Tandem mass spectrometric analysis of novel caffeine scaffold-based bifunctional compounds for Parkinson's disease.

Nwabufo CK, El-Aneed A, Krol ES. Nwabufo CK, et al. Among authors: krol es. Rapid Commun Mass Spectrom. 2019 Dec 15;33(23):1792-1803. doi: 10.1002/rcm.8540. Rapid Commun Mass Spectrom. 2019. PMID: 31351020

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