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First-in-Class Dual Mechanism Ferroptosis-HDAC Inhibitor Hybrids.
Karaj E, Sindi SH, Kuganesan N, Koranne RA, Knoff JR, James AW, Fu Y, Kotsull LN, Pflum MK, Shah Z, Taylor WR, Tillekeratne LMV. Karaj E, et al. Among authors: kuganesan n. J Med Chem. 2022 Nov 10;65(21):14764-14791. doi: 10.1021/acs.jmedchem.2c01276. Epub 2022 Oct 28. J Med Chem. 2022. PMID: 36306372 Free PMC article.
Small-Molecule Ferroptotic Agents with Potential to Selectively Target Cancer Stem Cells.
Taylor WR, Fedorka SR, Gad I, Shah R, Alqahtani HD, Koranne R, Kuganesan N, Dlamini S, Rogers T, Al-Hamashi A, Kholodovych V, Barudi Y, Junk D, Rashid MS, Jackson MW, Tillekeratne LMV. Taylor WR, et al. Among authors: kuganesan n. Sci Rep. 2019 Apr 11;9(1):5926. doi: 10.1038/s41598-019-42251-5. Sci Rep. 2019. PMID: 30976078 Free PMC article.