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Combining PARP with ATR inhibition overcomes PARP inhibitor and platinum resistance in ovarian cancer models.
Kim H, Xu H, George E, Hallberg D, Kumar S, Jagannathan V, Medvedev S, Kinose Y, Devins K, Verma P, Ly K, Wang Y, Greenberg RA, Schwartz L, Johnson N, Scharpf RB, Mills GB, Zhang R, Velculescu VE, Brown EJ, Simpkins F. Kim H, et al. Among authors: kumar s. Nat Commun. 2020 Jul 24;11(1):3726. doi: 10.1038/s41467-020-17127-2. Nat Commun. 2020. PMID: 32709856 Free PMC article.
A B7-H4-Targeting Antibody-Drug Conjugate Shows Antitumor Activity in PARPi and Platinum-Resistant Cancers with B7-H4 Expression.
Gitto SB, Whicker M, Davies G, Kumar S, Kinneer K, Xu H, Lewis A, Mamidi S, Medvedev S, Kim H, Anderton J, Tang EJ, Ferman B, Coats S, Wilkinson RW, Brown E, Powell DJ Jr, Simpkins F. Gitto SB, et al. Among authors: kumar s. Clin Cancer Res. 2024 Apr 15;30(8):1567-1581. doi: 10.1158/1078-0432.CCR-23-1079. Clin Cancer Res. 2024. PMID: 37882675
Loss of ELF5-FBXW7 stabilizes IFNGR1 to promote the growth and metastasis of triple-negative breast cancer through interferon-γ signalling.
Singh S, Kumar S, Srivastava RK, Nandi A, Thacker G, Murali H, Kim S, Baldeon M, Tobias J, Blanco MA, Saffie R, Zaidi MR, Sinha S, Busino L, Fuchs SY, Chakrabarti R. Singh S, et al. Among authors: kumar s. Nat Cell Biol. 2020 May;22(5):591-602. doi: 10.1038/s41556-020-0495-y. Epub 2020 Apr 13. Nat Cell Biol. 2020. PMID: 32284542 Free PMC article.
Estrogen Receptor β-Mediated Inhibition of Actin-Based Cell Migration Suppresses Metastasis of Inflammatory Breast Cancer.
Thomas C, Karagounis IV, Srivastava RK, Vrettos N, Nikolos F, Francois N, Huang M, Gong S, Long Q, Kumar S, Koumenis C, Krishnamurthy S, Ueno NT, Chakrabarti R, Maity A. Thomas C, et al. Among authors: kumar s. Cancer Res. 2021 May 1;81(9):2399-2414. doi: 10.1158/0008-5472.CAN-20-2743. Epub 2021 Jan 29. Cancer Res. 2021. PMID: 33514514 Free PMC article.
Author Correction: Loss of ELF5-FBXW7 stabilizes IFNGR1 to promote the growth and metastasis of triple-negative breast cancer through interferon-γ signalling.
Singh S, Kumar S, Srivastava RK, Nandi A, Thacker G, Murali H, Kim S, Baldeon M, Tobias J, Blanco MA, Saffie R, Zaidi MR, Sinha S, Busino L, Fuchs SY, Chakrabarti R. Singh S, et al. Among authors: kumar s. Nat Cell Biol. 2021 Sep;23(9):1048. doi: 10.1038/s41556-021-00733-7. Nat Cell Biol. 2021. PMID: 34349253 No abstract available.
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