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Repression of LSD1 potentiates homologous recombination-proficient ovarian cancer to PARP inhibitors through down-regulation of BRCA1/2 and RAD51.
Tao L, Zhou Y, Pan X, Luo Y, Qiu J, Zhou X, Chen Z, Li Y, Xu L, Zhou Y, Zuo Z, Liu C, Wang L, Liu X, Tian X, Su N, Yang Z, Zhang Y, Gou K, Sang N, Liu H, Zou J, Xiao Y, Zhong X, Xu J, Yang X, Xiao K, Liu Y, Yang S, Peng Y, Han J, Cen X, Zhao Y. Tao L, et al. Among authors: gou k. Nat Commun. 2023 Nov 16;14(1):7430. doi: 10.1038/s41467-023-42850-x. Nat Commun. 2023. PMID: 37973845 Free PMC article.
DHODH and cancer: promising prospects to be explored.
Zhou Y, Tao L, Zhou X, Zuo Z, Gong J, Liu X, Zhou Y, Liu C, Sang N, Liu H, Zou J, Gou K, Yang X, Zhao Y. Zhou Y, et al. Among authors: gou k. Cancer Metab. 2021 May 10;9(1):22. doi: 10.1186/s40170-021-00250-z. Cancer Metab. 2021. PMID: 33971967 Free PMC article. Review.
Discovery and Optimization of Novel hDHODH Inhibitors for the Treatment of Inflammatory Bowel Disease.
Zhou X, Gou K, Xu J, Jian L, Luo Y, Li C, Guan X, Qiu J, Zou J, Zhang Y, Zhong X, Zeng T, Zhou Y, Xiao Y, Yang X, Chen W, Gao P, Liu C, Zhou Y, Tao L, Liu X, Cen X, Chen Q, Sun Q, Luo Y, Zhao Y. Zhou X, et al. Among authors: gou k. J Med Chem. 2023 Nov 9;66(21):14755-14786. doi: 10.1021/acs.jmedchem.3c01365. Epub 2023 Oct 23. J Med Chem. 2023. PMID: 37870434
Pharmacological inhibition of LSD1 suppresses growth of hepatocellular carcinoma by inducing GADD45B.
Sang N, Zhong X, Gou K, Liu H, Xu J, Zhou Y, Zhou X, Liu Y, Chen Z, Zhou Y, Li Y, Tao L, Su N, Zhou L, Qiu J, Yang X, Zuo Z, Fu L, Zhang J, Li D, Li C, Sun Q, Lei J, Li R, Yang S, Cen X, Zhao Y. Sang N, et al. Among authors: gou k. MedComm (2020). 2023 May 24;4(3):e269. doi: 10.1002/mco2.269. eCollection 2023 Jun. MedComm (2020). 2023. PMID: 37250145 Free PMC article.
18 results