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6β-Hydroxycortisol is an endogenous probe for evaluation of drug-drug interactions involving a multispecific renal organic anion transporter, OAT3/SLC22A8, in healthy subjects.
Imamura Y, Tsuruya Y, Damme K, Heer D, Kumagai Y, Maeda K, Murayama N, Okudaira N, Kurihara A, Izumi T, Sugiyama Y, Kusuhara H. Imamura Y, et al. Among authors: kurihara a. Drug Metab Dispos. 2014 Apr;42(4):685-94. doi: 10.1124/dmd.113.055475. Epub 2014 Jan 31. Drug Metab Dispos. 2014. PMID: 24487120 Clinical Trial.
Prediction of fluoroquinolone-induced elevation in serum creatinine levels: a case of drug-endogenous substance interaction involving the inhibition of renal secretion.
Imamura Y, Murayama N, Okudaira N, Kurihara A, Okazaki O, Izumi T, Inoue K, Yuasa H, Kusuhara H, Sugiyama Y. Imamura Y, et al. Among authors: kurihara a. Clin Pharmacol Ther. 2011 Jan;89(1):81-8. doi: 10.1038/clpt.2010.232. Epub 2010 Dec 1. Clin Pharmacol Ther. 2011. PMID: 21124314 Clinical Trial.
214 results